Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.
Couldn't load pickup availability
Description
TCI C2226 Ceftriaxone Disodium Salt Hemiheptahydrate is the hydrated disodium salt form of ceftriaxone, a broad-spectrum third-generation cephalosporin antibiotic supplied here as a research reagent. The compound acts by inhibiting peptidoglycan synthesis in the bacterial cell wall, and it is well known for its long biological half-life, a characteristic that makes it interesting to study from both a microbiological and a pharmacological perspective. In the laboratory, ceftriaxone serves as one of the reference antibiotics used in susceptibility testing panels, resistance research, and the development of analytical methods.
Several properties make this particular salt form a preferred choice for laboratory work. The disodium hemiheptahydrate form offers excellent solubility in water, so concentrated stock solutions can be prepared without difficulty and sterilized directly by membrane filtration. The fixed water-of-crystallization content makes concentration calculations more accurate than they would be with material of undefined moisture content, which matters when a working solution has to be traceable to a stated weight. Its broad activity spectrum against both Gram-positive and Gram-negative bacteria makes it a versatile comparator across a wide range of test organisms. In recent years the compound has also been used extensively in neuroscience research, owing to its ability to modulate glutamate transporter expression in experimental models.
Indonesian laboratories typically encounter this material in university microbiology and pharmacy departments, hospital and clinical research laboratories, and quality control units working on antibiotic formulations. It is used to prepare reference solutions for susceptibility panels, to serve as a comparator strain-testing agent in antimicrobial resistance surveillance work, and to support method development for chromatographic and spectroscopic assays. Neuroscience and pharmacology groups working with animal or cell-culture models also draw on it for glutamate transporter studies.
Laboratory Applications
Antimicrobial susceptibility testing: serves as a reference third-generation cephalosporin in disc diffusion and broth dilution panels, where its well-characterised broad spectrum gives a dependable comparison point.
Antibiotic resistance research: used to challenge clinical and environmental isolates so that resistance mechanisms against cephalosporins can be characterised, screened, and monitored over successive passages.
Analytical method development: functions as a reference substance when building and validating chromatographic or spectroscopic assays for ceftriaxone, since its defined hydrate content supports accurate standard preparation.
Neuroscience research: applied in experimental models to modulate glutamate transporter expression, a use that has grown considerably in recent years across cell culture and animal studies.
Cell wall synthesis studies: employed to probe peptidoglycan biosynthesis inhibition in bacteria, allowing researchers to examine morphological and biochemical responses to beta-lactam exposure.
Specifications
Brand: TCI
CAS number: 104376-79-6
Category: Life Science > Biochemicals and Reagents > Antibiotics
Chemical form: disodium salt hemiheptahydrate of ceftriaxone
Pack sizes: available in standard TCI catalogue pack sizes; please confirm the specific size when ordering
Storage: keep in a cool, dry place in the tightly closed original container, protected from light and moisture
Handling and Storage
Store the material in its tightly closed original container in a cool, dry place, protected from light and moisture, since the defined water-of-crystallization content is central to accurate concentration calculations and should not be disturbed by ambient humidity. Allow the container to reach room temperature before opening to avoid condensation on the solid. Weigh and handle the powder in a fume hood or well-ventilated area, using gloves, safety glasses, and a laboratory coat, and avoid generating dust or inhaling airborne particles. Prepare aqueous stock solutions in clean glass or chemically compatible plasticware, sterilize by membrane filtration where a sterile solution is required, and label all solutions clearly with concentration and preparation date. Consult the manufacturer's safety data sheet before use and follow institutional procedures for the disposal of antibiotic-containing waste.
Sold out
