Cefditoren Pivoxil TCI C2856

Chemical Identity

CAS No.: 117467-28-4
PubChem: CID 6437877·SID 253661532
Formula: C25H28N6O7S3
Molecular weight: 620.71 g/mol
Purity: >98.0%(HPLC)(T)
Reference databases: ChEBI·ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 2,2-dimethylpropanoyloxymethyl (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
SMILES: CC1=C(SC=N1)C=CC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)OCOC(=O)C(C)(C)C
InChIKey: AFZFFLVORLEPPO-UVYJNCLZSA-N
MDL: MDL00933166

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Berat 200mg

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Cefditoren Pivoxil is a third-generation cephalosporin antibiotic supplied as a pivaloyloxymethyl ester prodrug. In biological systems, the ester group is hydrolysed to release cefditoren, the active form that acts against bacteria. As a member of the beta-lactam family, cefditoren inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). In the laboratory, this TCI product (C2856) serves as a reference standard and research material for microbiology, pharmacology, and the development of analytical methods for pharmaceutical compounds.

Researchers choose Cefditoren Pivoxil because it is a clear example of an ester prodrug designed to improve the oral absorption of a cephalosporin. This makes it a useful subject for studies of stability, ester hydrolysis, and pharmacokinetics. Its characteristic beta-lactam structure also suits research on antibiotic resistance, including its interaction with beta-lactamase enzymes. In pharmaceutical analysis, the compound is used to build and validate chromatographic methods, dissolution tests, and impurity tests. It is supplied as a solid, so it is easy to weigh accurately when preparing standard solutions.

In Indonesia, Cefditoren Pivoxil is useful to pharmaceutical laboratories, university research groups, and quality control units that work with beta-lactam antibiotics. Analysts use it to develop and verify methods for cephalosporin products. Microbiology researchers use it in susceptibility and resistance studies, and pharmacology teams use it to study how prodrugs are converted. Because it comes from TCI, a recognised reagent brand, laboratories have a consistent material for routine analytical work as well as exploratory research projects.

TCI brochures (PDF)

Antimicrobials and Antitumor Agents for Research and Experimental Use 2025-04-24 · p. 3
Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 3

Related TCI products

Reference standard for chromatography: suited to developing and validating HPLC methods for cephalosporins because the defined solid can be weighed precisely into standard solutions.
Prodrug hydrolysis studies: the pivaloyloxymethyl ester that releases active cefditoren makes it a good model for studying ester cleavage, stability, and prodrug activation.
Antibiotic resistance research: its beta-lactam structure allows researchers to study interactions with beta-lactamase enzymes and the mechanisms bacteria use to resist cephalosporins.
Microbiology and mechanism studies: as a PBP-binding inhibitor of cell wall synthesis, it supports experiments on how third-generation cephalosporins act against bacterial targets.
Dissolution and impurity testing: pharmaceutical analysts use it to establish dissolution methods and impurity profiles when they develop or verify quality control procedures for oral cephalosporins.

Brand	TCI (product code C2856)
CAS number	117467-28-4
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Antibiotics
Pack sizes	Available in TCI's standard pack sizes. See the product listing for current options.
Physical form	Solid
Storage	Follow the storage conditions on the TCI label and Safety Data Sheet

Store Cefditoren Pivoxil in its original, tightly closed container in a cool, dry place away from direct light and moisture. Always follow the specific storage conditions stated on the TCI label and Safety Data Sheet. Because the compound is an ester prodrug, exposure to humidity can promote hydrolysis, so reseal the container promptly after each use. When weighing the solid, wear gloves, a lab coat, and eye protection. Avoid creating or breathing in dust. Take extra care because beta-lactam antibiotics can trigger sensitisation in allergic individuals. Prepare standard solutions fresh where possible, label them clearly, and dispose of waste according to institutional and local regulations.

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