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Description
TCI C2990 2-(4-Chlorophenyl)-4,5-diphenylimidazole, CAS number 5496-32-2, is an aryl-substituted imidazole belonging to the lophine family, a group of 2,4,5-triarylimidazole derivatives. Its core structure consists of a five-membered imidazole ring bearing three aromatic groups, one of which carries a chlorine substituent. In the laboratory, compounds of this type serve as reagents and reference compounds in the development of detection systems, including methods related to the labelling and observation of nucleic acids. The triarylimidazole scaffold is widely recognized in organic chemistry for its interesting photophysical behaviour and the ease with which it can be modified into other derivatives.
The property that makes this compound a preferred choice is the extended conjugated system formed by the imidazole ring together with the three surrounding aromatic rings. This conjugation gives rise to characteristic light absorption and emission behaviour, allowing the compound to take part in luminescence and chemiluminescence studies. The chlorine substituent on one of the phenyl rings shifts the electronic character of the molecule while simultaneously providing a position for further functionalization. The imidazole ring also contains nitrogen atoms that can act as a weak base, adding a further handle for chemical manipulation and derivatization work.
In Indonesian laboratories, this material is typically encountered in university research groups, molecular biology facilities, and analytical chemistry units working on detection and hybridization methods. It fits into workflows where a well-characterized triarylimidazole is needed as a reference standard, a synthetic starting point, or a comparison compound during method development. Because it is supplied as a catalogue chemical from TCI, it suits teaching laboratories and research institutions that require consistent, identifiable material across repeated experiments.
Laboratory Applications
- Nucleic acid detection method development: the compound serves as a reagent and reference material in systems designed for labelling and observing nucleic acids, matching its assigned product category.
- Chemiluminescence studies: the extended conjugation across the imidazole and three aryl rings supports light-emission behaviour of the kind investigated in lophine-based chemiluminescent systems.
- Luminescence and photophysical characterization: characteristic absorption and emission arising from the conjugated triarylimidazole framework make it a useful subject or standard in optical measurement work.
- Synthetic derivatization chemistry: the chlorine substituent on one phenyl ring provides a defined position for further functionalization, allowing researchers to build new triarylimidazole derivatives.
- Reference compound in analytical work: as a defined catalogue substance with a specific CAS identity, it supports method comparison, calibration checks, and structural confirmation during analysis.
Specifications
- Brand: TCI
- CAS number: 5496-32-2
- Chemical name: 2-(4-Chlorophenyl)-4,5-diphenylimidazole
- Product code: C2990
- Category: Life Science > Molecular Biology > Nucleic Acid Detection and Hybridization
- Pack sizes and storage conditions: please refer to the manufacturer's current catalogue listing and the accompanying product label
Handling and Storage
Store the container tightly closed in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and incompatible chemicals. Keep the material in its original manufacturer container or in a clean, clearly labelled chemical-resistant vessel, and confirm the storage temperature stated on the product label and safety data sheet before shelving. Handle the compound in a fume hood or a well-ventilated workspace using standard laboratory personal protective equipment, including a laboratory coat, chemical-resistant gloves, and safety glasses. Avoid generating dust, avoid contact with skin and eyes, and wash hands thoroughly after handling. Dispose of residues and contaminated materials in accordance with institutional chemical waste procedures and applicable local regulations.
