Chlormethiazole Hydrochloride TCI C3020

Name: TCI C3020 6001-74-7 Chlormethiazole Hydrochloride
Brand: TCI
SKU: TCI2510C302017946
Price: 2982000.0 IDR
Availability: InStock

Rp 2.982.000,00

Sale Sold out

Shipping calculated at checkout.

Berat 200mg 1g

Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.

Description

TCI C3020 Chlormethiazole Hydrochloride is the hydrochloride salt of chlormethiazole, a substituted thiazole-framework compound widely documented in the pharmacological literature as a GABA-A receptor modulator. Within this catalogue it is classified as a heterocyclic building block — a molecular construction material that supplies researchers with a ready-to-use thiazole core for synthetic work. The thiazole ring is an important motif in medicinal chemistry because the presence of both a nitrogen and a sulfur atom within a single five-membered aromatic ring gives target molecules a distinctive hydrogen-bonding pattern and characteristic electronic interactions.

The property that makes this material a preferred choice is the combination of a stable heterocyclic core with a reactive chloroethyl side chain. That group provides an electrophilic site for nucleophilic substitution, allowing researchers to attach amines, thiols, or other nucleophiles in order to construct new derivatives. The hydrochloride salt form offers practical advantages: it is a solid that is easy to weigh out, is generally more soluble in water than the corresponding free base, and tends to be more stable during storage. Availability in 200 mg and 1 g packs makes it straightforward to match the quantity to the scale of the work.

In Indonesian laboratories this type of reagent is typically used in university and institutional synthetic chemistry groups, in medicinal chemistry and drug-discovery research where thiazole scaffolds are being explored, and in analytical work that requires a defined reference compound. The two available pack sizes suit both small exploratory reactions and repeated multi-step syntheses, so a group can order according to its actual consumption rather than committing to a larger quantity than the project needs.

Laboratory Applications

Heterocyclic derivative synthesis — the ready-made thiazole core removes the need to build the ring from scratch, saving synthetic steps and letting the chemist focus on the target modification.
Nucleophilic substitution chemistry — the chloroethyl side chain offers a well-defined electrophilic centre, so amines, thiols, and other nucleophiles can be coupled to generate a series of new analogues.
Medicinal chemistry scaffold exploration — the nitrogen- and sulfur-containing aromatic ring is a recognised pharmacophore motif, making the compound a practical starting point for structure–activity relationship studies.
Pharmacological research on GABA-A receptor modulation — chlormethiazole is well documented in the literature as a modulator of this receptor, supporting mechanistic and comparative neuropharmacology studies.
Analytical and reference work — the hydrochloride salt is an easily weighed solid, which suits the preparation of standard solutions and the identity confirmation of related thiazole compounds.

Specifications

Brand: TCI
CAS number: 6001-74-7
Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes: 200 mg and 1 g
Physical form: solid (hydrochloride salt)
Storage: keep in the tightly closed original container, protected from moisture; follow the storage conditions stated by the manufacturer on the label and safety data sheet

Handling and Storage

Store the material in its original, tightly closed container in a cool, dry place away from moisture, direct sunlight, and sources of heat or ignition, and follow the specific conditions given by the manufacturer on the product label and safety data sheet. Amber glass or the supplied container is suitable; keep the closure sealed between uses because the hydrochloride salt can take up atmospheric moisture. Handle in a fume hood, wear gloves, safety glasses, and a laboratory coat, and avoid inhaling dust or allowing contact with skin and eyes. Weigh out the solid carefully to minimise dust generation, label all prepared solutions clearly, and dispose of residues and contaminated consumables through the laboratory's chemical waste procedure. Read the safety data sheet in full before first use.