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Description
TCI C3054 2-Chloro-1,4-phenylenediamine is an aromatic compound carrying two amine groups in the para position on the benzene ring, together with a single chlorine atom as an additional substituent. It belongs to the class of non-heterocyclic building blocks, meaning it serves as a starting material used to assemble target molecules through reactions at its amine functional groups. Because it carries two amine groups, the compound is difunctional, which makes it particularly useful in polycondensation reactions, in the construction of heterocyclic rings, and in the synthesis of coloured compounds that require two reaction points on a single molecule.
The property that makes this material a preferred choice is the dual reactivity of its two amine groups, which can react with carboxylic acids, acid chlorides, aldehydes, and dicarbonyl compounds. The chlorine substituent on the ring exerts an electronic effect that lowers the aromatic electron density in a controlled manner, so the basicity and reactivity of the two amines can be differentiated and exploited for selective reactions. The chlorine atom also adds mass and halogen character to the final product, a feature frequently used to tune colour, solubility, and thermal stability in the resulting synthesised material.
In Indonesian laboratories, this building block is typically used in synthetic organic chemistry work at research institutes, universities, and industrial R&D units. It is generally handled at bench scale for the preparation of intermediates, for developing coloured compounds, and for producing polymer precursors. Because it is supplied as a defined TCI catalogue item, it fits routine laboratory workflows where a consistent, well-identified starting material is required for repeatable synthesis and method development.
Laboratory Applications
- Polycondensation reactions: the two para-oriented amine groups give the molecule two reaction points, allowing it to be chain-extended with difunctional partners to build polymer backbones.
- Heterocyclic ring formation: the amine groups react readily with dicarbonyl compounds and aldehydes, providing a direct route to fused nitrogen-containing ring systems from a simple aromatic precursor.
- Synthesis of coloured compounds: the para-diamine arrangement combined with the halogen substituent supports the preparation of dye and colourant structures where two reaction points on one molecule are required.
- Selective amine derivatisation: the chlorine substituent differentiates the basicity and reactivity of the two amine groups, allowing one amine to be functionalised preferentially before the other.
- Preparation of amide and imine intermediates: both amine groups couple with carboxylic acids, acid chlorides, and aldehydes, making the compound a convenient starting point for multi-step intermediate synthesis.
Specifications
- Brand: TCI
- CAS number: 615-66-7
- Catalogue code: C3054
- Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
- Pack sizes: available in the pack sizes listed in the TCI catalogue for this item
- Storage note: store in a tightly closed container, protected from light and air, in a cool and well-ventilated area
Handling and Storage
Store the product in its original tightly closed container, kept in a cool, dry, and well-ventilated place away from direct sunlight and sources of heat or ignition. Aromatic amines are sensitive to air and light, so containers should be resealed promptly after use and kept away from oxidising agents and acids. Handle the material inside a fume hood using nitrile gloves, safety glasses, and a laboratory coat, and avoid inhalation of dust or direct skin contact. Weigh and transfer with clean, dry, dedicated spatulas, clean any spills immediately, and dispose of residues and contaminated consumables through your institution's chemical waste procedure. Always consult the manufacturer's safety data sheet before first use.
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