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Description
TCI C3069 4-Chloro-2-methylbenzyl Alcohol is a non-heterocyclic aromatic compound carrying a hydroxymethyl group (a benzylic alcohol) on a benzene ring that bears both chlorine and methyl substituents. It belongs to the family of versatile building blocks, because the benzylic alcohol group is one of the most flexible transformation points available in organic synthesis. In the laboratory, this material is used as an intermediate for constructing the side chains of larger molecules, whether through oxidation, substitution, or the ether- and ester-forming reactions routinely carried out at research scale.
The property that makes this compound a preferred choice is the high yet controllable reactivity of its benzylic group. A benzylic alcohol can be selectively oxidised to the corresponding aldehyde, or taken further to a carboxylic acid; it can be converted into a benzyl halide or a sulfonate ester that is strongly reactive toward nucleophiles; and it can be esterified or etherified directly. The chlorine and methyl substituents on the ring impose a specific substitution pattern, so that derivatives prepared from it differ in geometry and electronic character from those made from simple benzyl alcohol analogues.
In Indonesian laboratories, this substitution pattern makes the material a practical starting point for synthetic and methodology work at research scale. It is typically handled in university organic chemistry laboratories, in research institute synthesis groups, and in industrial R&D units that prepare derivative libraries or reference materials. Because it functions as an intermediate rather than a finished reagent, it is usually ordered in the pack size that matches a defined series of experiments and used step by step within a documented synthetic route.
Laboratory Applications
Building block synthesis — the benzylic alcohol group provides a ready attachment point for extending molecular frameworks, letting researchers assemble larger target structures from a defined and reproducible starting material.
Selective oxidation studies — the benzylic position can be oxidised in a controlled manner to the aldehyde or onward to the carboxylic acid, making the compound suitable for evaluating oxidising systems and reaction selectivity.
Preparation of reactive intermediates — conversion of the alcohol into the corresponding benzyl halide or sulfonate ester yields species highly reactive toward nucleophiles, supporting subsequent substitution chemistry in multi-step routes.
Ether and ester formation — direct etherification or esterification of the hydroxymethyl group allows researchers to install linkers, protecting groups, or functional side chains under conditions common at research scale.
Structure–property comparison work — the specific chlorine and methyl substitution pattern gives derivatives a geometry and electronic profile distinct from simple benzyl alcohol analogues, which is useful when comparing structural variants.
Specifications
Brand: TCI
CAS number: 129716-11-6
Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Product code: C3069
Pack sizes: available in the research-scale pack sizes listed for this catalogue item
Storage: keep in a tightly closed container in a cool, dry, well-ventilated place
Handling and Storage
Store the container tightly closed in a cool, dry and well-ventilated area, away from direct sunlight, heat sources, and strong oxidising agents. Keep the material in its original supplier container, or in a clean, chemically compatible and clearly labelled glass container if it must be transferred. Handle in a fume hood using appropriate personal protective equipment, including gloves, safety glasses, and a laboratory coat, and avoid contact with skin and eyes as well as inhalation of dust or vapour. Reseal the container immediately after use to limit moisture uptake and contamination, record each withdrawal in the laboratory inventory, and consult the manufacturer's safety data sheet before first use and before disposal of any residue.
