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Description
TCI Cefdinir, supplied under catalogue code C3111, is an orally active third-generation cephalosporin antibiotic that has been well documented in the pharmacological literature for many years. As a laboratory material, this compound is used as a reference substance in microbiological testing, in the development of analytical methods, and in formulation research. Its core structure consists of a beta-lactam ring fused to a dihydrothiazine ring, together with an aminothiazolyl oxime side chain that gives it the characteristic activity profile associated with advanced cephalosporins against bacterial pathogens.
The reason this compound is selected for laboratory work lies in its role as a well-documented reference molecule. In antimicrobial susceptibility testing, cefdinir serves as a comparator for evaluating new candidate compounds and for assessing resistance patterns in clinical isolates. In analytical laboratories, the material is used to construct calibration curves, to validate liquid chromatography methods, and to study degradation behaviour. Its reactive beta-lactam ring demands careful handling with respect to heat, humidity, and extreme pH conditions, which in turn makes it an interesting model for stability and compatibility studies.
In Indonesian laboratories, TCI C3111 is typically encountered in pharmaceutical quality control units, in university research groups working on antibiotics, and in microbiology laboratories that carry out routine susceptibility work. It is also applied in analytical method development laboratories where a documented cephalosporin standard is required, and in formulation research where the behaviour of a beta-lactam active ingredient must be characterised under controlled conditions.
Laboratory Applications
- Antimicrobial susceptibility testing — cefdinir acts as a documented comparator antibiotic, allowing new candidate compounds to be benchmarked and resistance patterns in clinical isolates to be assessed reliably.
- Liquid chromatography method validation — the compound provides a well-characterised reference substance for establishing calibration curves and confirming that chromatographic methods perform as intended.
- Degradation and stability studies — the reactive beta-lactam ring responds measurably to heat, humidity, and extreme pH, making this material a useful model for stability investigations.
- Formulation research — as a third-generation cephalosporin active ingredient, it supports studies of compatibility and behaviour when beta-lactam antibiotics are incorporated into developmental formulations.
- Reference standard in microbiological testing — its long-standing documentation in the pharmacological literature makes it dependable for comparison work across routine and research microbiology protocols.
Specifications
- Brand: TCI
- CAS number: 91832-40-5
- Catalogue code: C3111
- Category: Life Science > Biochemicals and Reagents > Antibiotics
- Pack sizes: available in the standard laboratory pack sizes listed for this catalogue code; please confirm the required size when ordering.
- Storage note: store under cool, dry conditions away from heat, moisture, and extreme pH environments.
Handling and Storage
Store TCI C3111 Cefdinir in a cool, dry place, protected from heat, humidity, and light, and keep the container tightly closed at all times to limit moisture uptake. Use tightly sealed containers of chemically compatible material, and return the product to storage promptly after weighing so that exposure to ambient air is kept short. Because the beta-lactam ring is reactive, avoid contact with extreme pH conditions and elevated temperatures during preparation and handling. Wear a laboratory coat, gloves, and eye protection when working with the powder, weigh it in a well-ventilated area or fume hood to avoid inhalation of dust, and observe standard laboratory hygiene practices. Always consult the manufacturer's safety data sheet before use, and dispose of residues and contaminated consumables in accordance with applicable laboratory waste procedures.
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