TCI
2-(4-Chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane TCI C3500
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Description
2-(4-Chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is an organoboron compound widely used in organic chemistry laboratories. It serves as a key reagent in various synthetic processes, particularly in the construction of aromatic and heterocyclic compounds. This compound is a versatile tool in modern synthetic chemistry due to its ability to participate in multiple reaction pathways. Its role as a boronic acid derivative makes it especially valuable in cross-coupling reactions, where it facilitates the formation of carbon-carbon bonds with high efficiency and selectivity.
The compound's unique chemical structure and reactivity make it a preferred choice for chemists working in both academic and industrial settings. The presence of a chloro group on the aromatic ring enhances its reactivity and allows for targeted chemical transformations. Its stability under controlled conditions ensures reliable performance in laboratory experiments, while its reactivity enables the synthesis of complex molecular structures. These properties make it an essential component in the development of new pharmaceuticals and advanced materials.
In Indonesian laboratories, this compound is commonly used in organic synthesis research, particularly in academic institutions and research centers. Its application spans across various fields, including pharmaceutical development, material science, and chemical engineering. Due to its reactivity and utility, it is frequently utilized in projects involving the synthesis of bioactive compounds and functional materials. Its presence in Indonesian laboratories underscores its importance in advancing chemical research and innovation.
Laboratory Applications
- Suzuki Coupling Reactions: This compound is ideal for Suzuki coupling due to its ability to form stable boronic acid derivatives, enabling efficient cross-coupling with aryl halides to create complex aromatic structures.
- Kumada Coupling Reactions: It serves as a valuable reagent in Kumada coupling, where it facilitates the formation of carbon-carbon bonds through the use of organomagnesium reagents, enhancing synthetic versatility.
- Synthesis of Heterocyclic Compounds: Its reactivity allows for the selective formation of heterocyclic rings, making it a preferred choice in the synthesis of bioactive molecules and pharmaceutical intermediates.
- Organic Synthesis Research: It is widely used in research settings to develop new synthetic methodologies and explore novel reaction mechanisms in organic chemistry.
- Material Science Applications: Its ability to participate in cross-coupling reactions makes it useful in the synthesis of advanced materials, including polymers and functional coatings.
Specifications
- Brand: TCI
- CAS Number: 195062-61-4
- Category: Chemistry > Organometallic Reagents > Organoboron [Organometallic Reagents]
- Pack Sizes: Available in various quantities as per standard laboratory supply formats
- Physical Form: Solid powder
- Storage Note: Store in a cool, dry place away from moisture and direct sunlight
Handling and Storage
This compound should be stored in a cool, dry environment to maintain its stability and reactivity. It is recommended to use airtight containers to prevent exposure to moisture and air, which can affect its chemical integrity. As an organoboron compound, it is sensitive to moisture and should be handled with care to avoid unintended reactions. In laboratory settings, it is advisable to use gloves and appropriate personal protective equipment when handling this material. Proper labeling and storage conditions are essential to ensure safety and maintain the compound's effectiveness in chemical reactions. Always ensure that the storage area is well-ventilated and free from potential contaminants to preserve the compound's quality and performance.
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