TCI
2-(2-Chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane TCI C3612
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Description
2-(2-Chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a versatile organoboron compound widely used in organic synthesis, particularly in coupling reactions such as Suzuki and Kumada. This reagent plays a crucial role in the development of complex molecules by enabling the formation of carbon-carbon bonds under controlled conditions. Its unique structure, featuring a chloro group on the phenyl ring and a tetramethyl group on the dioxaborolan ring, makes it an essential component in the synthesis of heterocyclic compounds, pharmaceuticals, and industrial chemicals. In the laboratory, this compound is indispensable for reactions requiring high reactivity and specificity.
The compound's ability to coordinate with metals such as palladium makes it ideal for catalytic processes that require precise control over reaction mechanisms. Its reactivity is balanced by a degree of stability, allowing it to be used in a variety of reaction conditions, including low-temperature or anhydrous environments. This combination of reactivity and stability ensures that it remains a preferred choice for chemists working on challenging synthetic routes.
In Indonesian laboratories, this compound is commonly used in organic chemistry research, particularly in academic and research institutions focused on the synthesis of complex molecules. Its application spans across both academic and industrial research, supporting the development of new drugs, materials, and chemical processes. The compound's reliability and effectiveness make it a staple in many laboratory settings.
Laboratory Applications
- Organic synthesis of heterocyclic compounds due to its ability to form carbon-carbon bonds efficiently.
- Pharmaceutical research for the development of new drug molecules requiring precise coupling reactions.
- Industrial chemical production where stable and reactive reagents are needed for complex syntheses.
- Academic research in universities focusing on advanced organic chemistry techniques and methodologies.
- Catalytic processes involving palladium-based reactions that require organoboron reagents for enhanced efficiency.
Specifications
- Brand: TCI
- CAS number: 870195-94-1
- Category: Chemistry > Organometallic Reagents > Organoboron [Organometallic Reagents]
- Pack sizes: Available in various sizes as per supplier specifications
- Physical form: Solid or liquid, depending on the specific formulation
- Storage note: Store in a cool, dry place away from moisture and light
Handling and Storage
This compound should be stored in a cool, dry place, away from moisture and direct light to maintain its stability and reactivity. It is recommended to use airtight containers made of materials such as glass or polyethylene to prevent contamination and degradation. Due to its reactivity, it should be handled with care, using appropriate personal protective equipment. In laboratory settings, it is important to ensure proper ventilation and avoid exposure to incompatible substances. Always follow standard safety protocols to minimize risks during handling and storage.
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