Capsazepine, with CAS number 138977-28-3, is a chemical compound widely used in life science research, particularly in the study of apoptosis or programmed cell death. As an agonist of the TRPV1 receptor, it plays a crucial role in investigating pain and inflammation responses. In laboratory settings, it serves as a valuable tool for inducing or observing apoptotic processes, making it essential for studies related to cancer and neurodegenerative diseases. Its chemical stability and solubility in organic solvents such as ethyl acetate or acetone contribute to its versatility in various experimental protocols.
Capsazepine is preferred due to its consistent chemical properties and compatibility with common laboratory techniques. Its solubility in organic solvents allows for easy preparation of solutions for experiments like ELISA, Western blot, and enzyme activity assays. The compound’s stability under standard laboratory conditions ensures reliable results across multiple experiments. Additionally, its availability in small pack sizes, such as 10 mg, supports precise usage in controlled environments, enhancing reproducibility and accuracy in research.
In Indonesian laboratories, Capsazepine is commonly used in biomedical and pharmacological research. It is a key component in studies exploring the mechanisms of cell death and in the development of new therapeutic agents. Its application in both academic and industrial research settings highlights its importance in advancing scientific understanding and innovation in the field of life sciences.
- Apoptosis Research: Capsazepine is used to study programmed cell death mechanisms, aiding in understanding cancer and neurodegenerative disease progression.
- Pain and Inflammation Studies: It acts as a TRPV1 receptor agonist, helping researchers explore the physiological responses related to pain and inflammation.
- ELISA and Western Blot Analysis: Its solubility in organic solvents makes it suitable for preparing samples for these sensitive detection techniques.
- Enzyme Activity Assays: The compound is used to test the activity of enzymes involved in apoptotic pathways, supporting biochemical investigations.
- Drug Development: It is a key reagent in the development of new therapeutic agents targeting TRPV1-related pathways in disease models.
| Brand | TCI |
|---|---|
| CAS number | 138977-28-3 |
| Molecular formula | — |
| Purity | — |
| Category | Life Science > Cell Biology > Apoptosis |
| Pack sizes | 10 mg |
| Physical form | Solid |
| Storage | Store in a cool, dry place away from light |
Capsazepine should be stored in a cool, dry place, away from direct light to maintain its chemical stability. It is recommended to use airtight containers to prevent moisture absorption and contamination. Due to its solubility in organic solvents, it should be handled in a well-ventilated area to minimize exposure. When working with the compound, laboratory personnel should wear appropriate personal protective equipment, such as gloves and safety goggles. Capsazepine is not flammable, but it should be kept away from incompatible substances. Proper labeling and storage practices are essential to ensure safe handling and long-term usability in research settings.
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