Cyclopent-3-en-1-ol from TCI is a five-membered cyclic alcohol. It has one carbon-carbon double bond at position 3 and a secondary hydroxyl group at position 1. The molecule is small but carries two different functional groups, which makes it a very useful non-heterocyclic building block. In the laboratory it serves as a starting material for building substituted cyclopentane frameworks. These frameworks form the core of many natural products and pharmaceutical molecules, so the compound is a practical entry point for multi-step synthetic routes.
The double bond sits symmetrically relative to the hydroxyl group, which gives the molecule a plane of symmetry. This makes it especially attractive for desymmetrization reactions and stereoselectivity studies. The double bond can be oxidized, epoxidized, dihydroxylated, or subjected to addition reactions. The hydroxyl group can be protected, oxidized to a ketone, or used to direct the stereochemistry of reactions at the double bond. Together, these two reactive sites open many transformation pathways from one simple starting material, so chemists can reach diverse target structures with fewer separate reagents.
For organic synthesis laboratories in Indonesia, this compound is relevant to research on carbocyclic nucleoside analogues, prostaglandins, and five-membered-ring natural products. University research groups, pharmaceutical development laboratories, and graduate thesis projects that focus on synthetic methodology or medicinal chemistry can use it as a dependable precursor. The 5 g pack is enough for a series of small-scale experiments, including route scouting and method optimization, before work moves on to larger preparative batches.
Related TCI products
- Desymmetrization studies: the molecule's plane of symmetry makes it a good substrate for testing enantioselective catalysts and methods that turn a symmetric starting material into a chiral product.
- Synthesis of carbocyclic nucleoside analogues: the functionalized cyclopentene ring gives a suitable carbocyclic core that can be built up into nucleoside mimics for medicinal chemistry research.
- Prostaglandin and natural product synthesis: the five-membered ring with an alkene and a hydroxyl group matches the core motifs found in prostaglandins and many cyclopentanoid natural products.
- Hydroxyl-directed stereoselective reactions: the secondary hydroxyl group can guide epoxidation or dihydroxylation onto one face of the double bond, which makes the compound useful for teaching and studying stereocontrol.
- Functional group transformation practice: the alcohol can be protected or oxidized to a ketone while the alkene stays available, so it suits advanced organic chemistry coursework and methodology development.
| Brand | TCI (product code C3992) |
|---|---|
| CAS number | 14320-38-8 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Non-Heterocyclic Building Blocks |
| Pack sizes | 5 g |
| Physical form | see the TCI certificate of analysis and Safety Data Sheet |
| Storage | follow the conditions on the TCI product label and SDS |
Store Cyclopent-3-en-1-ol in its original, tightly closed TCI container. Keep it in a cool, dry, well-ventilated chemical storage area, away from heat, ignition sources, and strong oxidizing agents. Follow the specific storage conditions on the product label and in the Safety Data Sheet. Handle the compound in a fume hood while wearing appropriate personal protective equipment, including safety goggles, chemical-resistant gloves, and a laboratory coat. Avoid inhalation and contact with skin and eyes. Reseal the container promptly after use to limit exposure to air and moisture. Label any transferred portions clearly, and dispose of waste according to institutional and local chemical waste regulations.
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