• 2,4-Dimethyl-6-hydroxypyrimidine (CAS 6622-92-0) - TCI D2579 - AMI Scientific
1 1

TCI

CAS 6622-92-0

2,4-Dimethyl-6-hydroxypyrimidine TCI D2579

2,4-Dimethyl-6-hydroxypyrimidine TCI D2579
Rp 768.600,00
Rp 768.600,00
Sale Sold out
Shipping calculated at checkout.
Berat
Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.

Dokumen Keamanan & Mutu

↓ Unduh SDS / MSDS (PDF resmi TCI)
CoA (Certificate of Analysis)

Spesifik per batch produksi — diterbitkan dan dikirim bersama barang sesuai nomor lot yang Anda terima.

Contoh CoA segera tersedia.

💬 Minta CoA via WhatsApp

View full details

TCI D2579 2,4-Dimethyl-6-hydroxypyrimidine is a heterocyclic building block from the pyrimidine family, a six-membered aromatic ring containing two nitrogen atoms. The compound carries two methyl groups and one hydroxyl group, and as is typical of hydroxypyrimidines, it can exist in a tautomeric equilibrium between the hydroxy form and the oxo form. In the laboratory, this material serves as a starting material for constructing substituted pyrimidine derivatives, a class of compounds of considerable importance because the pyrimidine scaffold forms the core of nucleotide bases as well as many drug molecules and agricultural active ingredients.

The characteristic that makes this compound a preferred choice is the ease with which it can be derivatised. The hydroxyl or oxo group on the ring can be converted into a chloride group using chlorinating reagents, producing a chlorinated pyrimidine that is highly reactive toward nucleophilic aromatic substitution as well as cross-coupling reactions. In this way, a single simple starting material can be directed toward a wide range of derivatives bearing amino, alkoxy, or aryl groups. The two methyl groups themselves contribute electronic and steric effects that direct reactivity, and under certain conditions they can be further functionalised.

In Indonesian laboratories, this building block is typically used in synthetic organic chemistry groups at universities and research institutes, in medicinal chemistry programmes exploring pyrimidine-based scaffolds, and in agrochemical research where pyrimidine cores appear frequently. It is also useful in method development work, where a well-defined heterocyclic substrate is needed to test chlorination, substitution, or coupling protocols before those procedures are applied to more valuable or more elaborate intermediates.

  • Synthesis of substituted pyrimidine derivatives: the ring offers a defined substitution pattern that allows chemists to build targeted analogues from a single, readily handled starting material.
  • Preparation of chlorinated pyrimidine intermediates: treatment with chlorinating reagents converts the hydroxy/oxo position into a chloride that is highly activated for downstream transformations.
  • Nucleophilic aromatic substitution studies: the chlorinated derivative reacts cleanly with amine, alkoxide, and other nucleophiles, giving access to amino- and alkoxy-substituted pyrimidines.
  • Cross-coupling reaction development: the halogenated derivative serves as a coupling partner for introducing aryl groups onto the pyrimidine ring in methodology work.
  • Medicinal and agrochemical research intermediates: because pyrimidine cores appear in nucleotide bases, drug molecules, and crop-protection actives, this scaffold supports exploratory synthesis in both fields.

Brand TCI
CAS number 6622-92-0
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes available in standard TCI research pack sizes; please confirm the currently listed options when ordering
Physical form —
Storage keep in a tightly closed container in a cool, dry, well-ventilated place
  • Chemical name: 2,4-Dimethyl-6-hydroxypyrimidine
  • Catalogue code: D2579

Store the material in its original tightly closed container in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, moisture, and incompatible substances. Glass bottles with well-sealing caps are suitable for storing and dispensing this solid; keep the container closed when not in use to limit exposure to atmospheric moisture. Handle the compound in a fume hood using standard laboratory personal protective equipment, including safety glasses, a laboratory coat, and chemically resistant gloves, and avoid the generation and inhalation of dust during weighing and transfer. Use clean, dry spatulas to prevent contamination of the bulk material, label all secondary containers clearly, and consult the manufacturer's Safety Data Sheet before use for the full hazard, first-aid, and disposal information applicable to your laboratory.

—

Produk Terkait