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Description
Deoxyribonucleic Acid Sodium Salt from Salmon Milt is a naturally derived, high-molecular-weight DNA isolated from salmon milt (the seminal fluid of salmon) and supplied as its sodium salt, a form that dissolves readily in water and remains stable during storage as a dry solid. In life science and materials science laboratories, this material serves as a bulk source of genomic DNA for work that does not require any specific nucleotide sequence. Researchers use it as a substrate for nuclease enzyme assays, as carrier or blocking DNA in hybridization experiments, as a test substrate for studying drug–DNA interactions, and as a biopolymer for fabricating DNA-based films, gels, and composite materials.
The property that makes this product a preferred choice is its availability as long, naturally occurring double-stranded DNA at a handling cost far lighter than that of synthetic oligonucleotides. Salmon milt is an exceptionally rich natural source of DNA, and the sodium salt form dissolves into a viscous solution that is straightforward to handle in aqueous buffers. The phosphate backbone of DNA carries a strong negative charge, so the material can be paired with cationic surfactants, metal ions, or positively charged polymers to form functional complexes. Its double-helical structure also provides binding sites that make it useful wherever a genuine nucleic acid scaffold is needed rather than a synthetic mimic.
In Indonesian laboratories, this reagent is typically used in university and institutional research settings where biochemistry, molecular biology, and materials chemistry groups need a dependable, non-sequence-specific DNA supply. It fits routine enzyme characterisation work, method development for hybridization protocols, and exploratory studies on DNA-binding compounds. Because it is supplied as a stable solid rather than a frozen solution, it suits facilities that prepare working solutions in-house as needed and store the bulk material long-term.
Laboratory Applications
- Nuclease enzyme assays — the material provides abundant natural double-stranded DNA as a cleavage substrate, allowing activity measurement without the expense of preparing sequence-defined synthetic templates.
- Hybridization blocking and carrier DNA — its non-specific, high-molecular-weight character lets it saturate non-target binding sites or carry trace nucleic acids through precipitation steps without interfering with the sequence of interest.
- Drug–DNA interaction studies — the intact double helix offers authentic intercalation and groove-binding sites, making it a realistic test substrate for screening how candidate compounds associate with nucleic acids.
- DNA-based films and gels — as a long-chain biopolymer it can be cast or crosslinked into self-supporting films and hydrogels, giving materials researchers a renewable natural polymer with defined charge behaviour.
- Polyelectrolyte complex formation — the strongly anionic phosphate backbone pairs readily with cationic surfactants, metal ions, or polycations, supporting the preparation of functional composite and optical materials.
Specifications
- Brand: TCI
- CAS Number: 9007-49-2
- Category: Life Science > Biochemicals and Reagents > Nucleosides, Nucleotides, Oligonucleotides
- Product Code: TCI D3545
- Physical Form: Solid, supplied as the sodium salt
- Storage: Store as a dry solid under the conditions stated on the manufacturer's label; pack sizes available on request
Handling and Storage
Keep the product in its original tightly closed container, stored as a dry solid and protected from moisture, since the sodium salt is hygroscopic in character and readily takes up water from humid air. Follow the storage temperature indicated on the manufacturer's label. Use clean, dry glass or inert plastic containers for weighing and for preparing aqueous stock solutions, and allow closed containers to reach room temperature before opening to limit condensation. Prepare solutions in aqueous buffer with gentle mixing, as concentrated solutions become viscous. Handle with standard laboratory practice: wear a lab coat, safety glasses, and gloves, work in a well-ventilated area, avoid generating dust when weighing the solid, and consult the manufacturer's safety data sheet before use. Aqueous solutions are susceptible to nuclease contamination, so prepare them with clean technique and store or divide them according to your laboratory's established protocol.
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