Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.
Description
TCI D3629, 1-(2,4-Dichlorophenyl)-2-(1-imidazolyl)ethanol, is an organic compound that combines a doubly chlorinated phenyl ring, a secondary hydroxyl group, and an imidazole ring within a single molecule. It belongs to the heterocyclic building blocks category, which means its role in the laboratory is to supply a ready-made heterocyclic framework for the preparation of more complex derivative compounds. This structure is widely recognised as the core scaffold of the azole class of antifungal agents, making the compound a practical starting point for chemists who study or develop antifungal analogues at research scale.
The properties that make this compound a preferred choice are the presence of three complementary functional groups. The secondary hydroxyl group can be etherified, esterified, or activated into a leaving group for subsequent substitution reactions, while the imidazole ring provides a basic nitrogen atom capable of coordinating with metals or interacting with the active sites of enzymes. The two chlorine atoms on the aromatic ring increase lipophilicity and stabilise the ring against oxidation. The molecule also carries a chiral centre at the hydroxyl-bearing carbon, which is relevant wherever stereochemistry influences the outcome of a synthesis.
In Indonesian laboratories, a compound of this type is normally used in university and institutional research settings rather than in routine analysis. It is typically handled at synthetic organic chemistry benches, in medicinal chemistry groups working on antifungal analogues, and in laboratories that prepare heterocyclic intermediates for further study. Because it is supplied as a defined building block, it is generally purchased in small research quantities and consumed across a series of derivatisation experiments rather than in bulk production.
Laboratory Applications
- Synthesis of azole antifungal analogues: the molecule already contains the dichlorophenyl and imidazole motifs of this compound class, so chemists can build derivatives without constructing the core scaffold themselves.
- Heterocyclic derivatisation chemistry: the secondary hydroxyl group can be etherified, esterified, or converted into a leaving group, giving several independent routes to structurally varied derivative compounds.
- Medicinal chemistry structure-activity studies: the combination of a basic imidazole nitrogen and a lipophilic dichlorinated ring allows researchers to explore how each fragment contributes to biological interaction.
- Coordination chemistry investigations: the imidazole nitrogen atom is able to coordinate with metal centres, making the compound useful when preparing or studying nitrogen-donor ligand systems.
- Stereochemistry-focused synthetic work: the chiral centre at the hydroxyl-bearing carbon lets laboratories examine how configuration at that position affects reaction outcomes and downstream product properties.
Specifications
- Brand: TCI (Tokyo Chemical Industry)
- CAS number: 24155-42-8
- Chemical name: 1-(2,4-Dichlorophenyl)-2-(1-imidazolyl)ethanol
- Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
- Pack sizes: available in standard research-scale packaging; please refer to the current catalogue listing for available options
- Storage: store according to the conditions stated on the manufacturer's label and safety data sheet
Handling and Storage
Store the material in its original tightly closed container, in a cool, dry, and well-ventilated area away from direct sunlight, heat sources, and incompatible chemicals such as strong oxidising agents. Amber glass or the manufacturer's supplied container is suitable for keeping the compound protected from light and moisture. Handle the product inside a fume hood using safety glasses, chemical-resistant gloves, and a laboratory coat, and avoid inhaling dust or generating aerosols. Weigh and transfer the solid with clean, dry equipment to prevent contamination, reseal the container immediately after use, and always consult the manufacturer's safety data sheet for the definitive storage temperature, handling requirements, and disposal procedures applicable in your laboratory.
