Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.
Description
TCI D4197, 3,5-Diphenylpyrazole with CAS number 1145-01-3, is a heterocyclic building block consisting of a five-membered pyrazole ring containing two nitrogen atoms, substituted with phenyl groups at the 3- and 5-positions. The pyrazole ring is one of the most important motifs in medicinal chemistry and coordination chemistry because of its ability to act simultaneously as a hydrogen bond donor and acceptor. In the laboratory, this compound is used as a starting material for constructing more complex target molecules, as a ligand in metal complexes, and as a component in the assembly of porous material frameworks.
The properties that make it a widely preferred choice include the presence of the N–H group on the pyrazole ring, which can be deprotonated to form a bridging pyrazolate ligand, making it highly useful for assembling polynuclear complexes as well as metal-organic frameworks. The two phenyl groups at the 3- and 5-positions provide balanced steric hindrance and extend the conjugated system, two factors that influence both the stability of the resulting complexes and their optical properties. Its substitution symmetry also simplifies the interpretation of nuclear magnetic resonance spectra. As a solid that is stable under ordinary storage conditions, the compound is practical to handle in routine laboratory work.
In Indonesian laboratories, 3,5-diphenylpyrazole is typically encountered in university and institutional research settings where synthetic organic chemistry, coordination chemistry, and materials chemistry are pursued. It serves research groups preparing ligands for metal complexes, teams exploring porous framework materials, and synthesis laboratories building heterocyclic scaffolds toward more elaborate target molecules. Because it is a stable solid requiring no special conditions beyond ordinary chemical storage, it fits well into the practical constraints of everyday laboratory operation.
Laboratory Applications
- Heterocyclic scaffold synthesis — serves as a starting material for constructing more complex target molecules, with the pyrazole core already established so that subsequent chemistry can focus on elaborating substituents.
- Ligand preparation for metal complexes — the pyrazole nitrogen atoms coordinate readily to metal centres, while the 3,5-phenyl substitution provides balanced steric hindrance that influences the stability of the resulting complexes.
- Polynuclear complex assembly — the N–H group on the pyrazole ring can be deprotonated to give a bridging pyrazolate ligand, making this compound well suited to linking several metal centres within one structure.
- Metal-organic framework construction — the same bridging pyrazolate capability allows this building block to be used as a component in the assembly of porous material framework structures.
- Medicinal chemistry research — the pyrazole ring is among the most important motifs in medicinal chemistry because it acts simultaneously as a hydrogen bond donor and acceptor in molecular recognition.
Specifications
- Brand: TCI
- CAS number: 1145-01-3
- Chemical name: 3,5-Diphenylpyrazole
- Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
- Physical form: solid, stable under ordinary storage conditions
- Pack sizes: available in the pack sizes offered by the manufacturer for this catalogue item
Handling and Storage
Store this compound as a solid under ordinary chemical storage conditions in a cool, dry, well-ventilated area away from direct sunlight, moisture, and incompatible materials. Keep it in its original tightly closed container, or transfer it to a clean, labelled glass or chemically compatible container that seals properly to prevent moisture uptake and contamination. Handle the solid inside a fume hood where dust may be generated, and wear standard laboratory personal protective equipment including safety goggles, a laboratory coat, and suitable chemical-resistant gloves. Use clean, dry spatulas when weighing to preserve the integrity of the remaining material, close containers immediately after use, and follow the manufacturer's safety data sheet together with your institution's chemical waste disposal procedures.
