4,4'-Di-tert-butylbenzophenone TCI D5308

Rp 4.015.200,00

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Berat 1g

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Description

4,4'-Di-tert-butylbenzophenone is an organic compound belonging to the benzophenone family, featuring two tert-butyl groups at the para positions of both aromatic rings. In laboratory practice, this material serves as a valuable synthetic building block for assembling more complex molecules such as diaryl ketone derivatives, pharmaceutical intermediates, functional monomers, and organic ligands. The presence of two bulky tert-butyl groups makes it particularly interesting for researchers who wish to study steric effects on carbonyl reactivity, as well as for the development of functional materials such as photoinitiators, UV absorbers, and fine chemical intermediates. This TCI product is supplied in 1 gram packaging, designed for small-scale research needs in organic chemistry, materials chemistry, and medicinal chemistry laboratories.

The compound's main strengths lie in its structural stability and the distinctive reactivity of the benzophenone carbonyl group, which can undergo nucleophilic addition reactions, reduction, and photochemical processes such as hydrogen abstraction. The two tert-butyl groups create substantial steric hindrance that influences reaction selectivity, giving synthetic chemists a useful handle for controlling the outcome of transformations involving the carbonyl moiety. This combination of stability and tunable reactivity makes it a preferred choice for researchers who need a well-defined, reproducible building block for route scouting, methodology development, and the preparation of functional materials. Its consistent performance as a high-quality research reagent further reinforces its position as a dependable option in synthetic chemistry workflows.

In Indonesian laboratories, this compound is typically used in academic and industrial research settings focused on organic synthesis, medicinal chemistry, and materials science. Researchers commonly employ it to construct sterically hindered diaryl systems, to probe structure-activity relationships, and to develop photoresponsive materials. Its 1 gram presentation suits the scale of most local research projects, allowing laboratories to evaluate the reagent in small pilot reactions before scaling up. The compound also fits well into graduate research programs and contract research activities that demand high-quality building blocks with reliable and reproducible behavior across repeated experiments.

Laboratory Applications

Synthesis of diaryl ketone derivatives: the benzophenone carbonyl provides a versatile electrophilic center that can be elaborated through nucleophilic addition and coupling strategies to build sterically hindered diaryl ketone frameworks.
Medicinal chemistry intermediates: the rigid, bulky diaryl structure serves as a scaffold for assembling pharmaceutical intermediates, where the tert-butyl groups help modulate lipophilicity and metabolic stability.
Functional monomer preparation: the reactive carbonyl can be converted into polymerizable functionalities, enabling the design of functional monomers for specialty polymers, coatings, and advanced materials.
Photochemical and photoinitiator studies: the benzophenone chromophore undergoes efficient hydrogen abstraction under UV irradiation, making this compound useful for studying photoinitiation behavior and UV-absorbing properties.
Steric effect investigations: the two bulky tert-butyl groups create defined steric environments around the carbonyl, allowing researchers to examine how steric hindrance influences reaction selectivity and kinetics.

Specifications

Brand: TCI
Product name: TCI D5308 4,4'-Di-tert-butylbenzophenone
CAS number: 15796-82-4
Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack size: 1 gram
Physical form: not specified in the available product data; keep container tightly closed when not in use

Handling and Storage

Store the product in its original, tightly sealed container in a cool, dry, and well-ventilated area, protected from direct sunlight and excessive humidity. Suitable containers include the manufacturer's original packaging or clean, dry laboratory glassware with secure, tight-fitting caps. As with all fine chemicals, avoid prolonged exposure to air and moisture once the container is opened. Wear appropriate personal protective equipment such as laboratory gloves and safety goggles when handling, and work in a fume hood whenever possible. Keep the material away from strong oxidizing agents and ignition sources, and clearly label any opened container with the product name and the date of opening to ensure safe traceability.