TCI
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Description
Etoposide is a chemical compound widely used in biochemical and pharmacological research. It belongs to a class of compounds with high biological activity, particularly in the inhibition of topoisomerase II, an enzyme critical in DNA replication and repair. In the laboratory, Etoposide plays a key role in studying drug mechanisms, toxicity testing, and the effects of compounds on human cells. Its importance extends to the development of anti-cancer drugs, where it serves as a vital active pharmaceutical ingredient. Due to its versatility and effectiveness, Etoposide is a common choice for researchers across various scientific disciplines.
Etoposide is chemically stable under certain conditions but is highly sensitive to light and high temperatures. It dissolves well in organic solvents such as ethyl acetate and acetone, making it easy to incorporate into chemical reactions and biochemical experiments. The compound’s high purity and consistent quality ensure reliable results, making it a preferred material for laboratory use. These properties contribute to its widespread application in both academic and industrial research settings.
In Indonesian laboratories, Etoposide is frequently utilized in cancer research, pharmacology, and biochemical studies. It is an essential tool for understanding drug mechanisms and developing new therapeutic approaches. Researchers in various institutions rely on Etoposide to advance their studies and contribute to scientific innovation in the field of medicinal chemistry.
Laboratory Applications
- Cancer research and drug development as it inhibits topoisomerase II, a key target in anti-cancer therapies.
- Pharmacological studies to evaluate the mechanism of action and biological effects of compounds on human cells.
- Toxicity testing to assess the safety and potential side effects of Etoposide in experimental models.
- Biochemical experiments involving DNA manipulation and enzyme activity analysis due to its interaction with topoisomerase II.
- Molecular biology research for studying DNA damage and repair processes in cellular systems.
Specifications
- Brand: TCI
- CAS number: 33419-42-0
- Category: Chemistry > Chemical Biology > Glycoscience
- Pack sizes: Available in various quantities as per standard laboratory supply
- Physical form: Solid powder
- Storage note: Store in a cool, dark place away from light and high temperatures
Handling and Storage
Etoposide should be stored in a cool, dark environment to prevent degradation due to light and heat exposure. It is recommended to keep the compound in a tightly sealed container to minimize exposure to air and moisture. When handling Etoposide, researchers should use appropriate personal protective equipment, such as gloves and safety goggles, to ensure safety. Due to its sensitivity, it is best to use small quantities at a time and avoid prolonged storage. Proper labeling and storage conditions are essential to maintain its stability and effectiveness in laboratory applications.
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