7-Ethyl-3-indoleethanol TCI E0824

TCI E0824 7-Ethyl-3-indoleethanol is an indole derivative carrying a 2-hydroxyethyl chain at the 3-position and an ethyl group at the 7-position. Its core skeleton is related to tryptophol, a naturally occurring compound derived from tryptophan metabolism and encountered across a range of biological systems. In the laboratory, this compound serves as a heterocyclic building block that supplies both an intact indole nucleus and a primary alcohol group ready for further elaboration, making it a practical entry point for constructing more complex molecules without assembling the indole ring from scratch.

The added value of this compound lies in its readily workable primary hydroxyl group. Primary alcohols can be oxidised to aldehydes or carboxylic acids, converted into leaving groups such as mesylates or tosylates for substitution reactions, esterified, or etherified. The 3-position of the indole ring is itself a characteristic nucleophilic centre, while the ethyl substituent at the 7-position introduces a degree of steric hindrance and lipophilicity that can influence the course of a reaction as well as the physicochemical properties of the final product. The indole nitrogen remains available for protection or substitution, giving researchers several independent handles on a single scaffold.

In Indonesian laboratories, materials of this type are typically used in university and institutional research groups working on organic synthesis, medicinal chemistry, and natural product chemistry, where indole-containing structures are frequently encountered. They are handled at bench scale for exploratory reaction development, methodology studies, and the preparation of intermediates that are subsequently characterised by routine analytical instrumentation available in the host laboratory.

• Heterocyclic building block in multistep organic synthesis, supplying a pre-formed indole nucleus so that research groups can begin elaboration immediately rather than constructing the ring system themselves.
• Functional group interconversion studies, where the primary alcohol is oxidised to the corresponding aldehyde or carboxylic acid to extend the molecule along a planned synthetic route.
• Substitution chemistry via activated intermediates, converting the hydroxyl group into a mesylate or tosylate leaving group so that nucleophiles can be introduced onto the side chain.
• Esterification and etherification work, in which the accessible primary hydroxyl serves as the reactive handle for coupling the indole fragment to acids, alcohols, or other partners.
• Medicinal chemistry and tryptophol-related research, taking advantage of the structural relationship to a tryptophan metabolite together with the 7-ethyl substituent that modifies steric and lipophilic character.

• Product code: E0824

Store the material in its original tightly closed container in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and incompatible chemicals, following the storage conditions stated on the manufacturer label and safety data sheet. Amber glass or the supplied original packaging is suitable for keeping the contents protected from light and moisture. Handle in a fume hood using appropriate personal protective equipment, including safety glasses, gloves, and a laboratory coat. Avoid inhalation of dust and contact with skin and eyes. Use clean, dry spatulas to prevent contamination, reseal the container promptly after each use, and dispose of residues and contaminated materials in accordance with institutional chemical waste procedures.

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