• E-64d [for Biochemical Research] (CAS 88321-09-9) - TCI E1337 - AMI Scientific
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TCI

CAS 88321-09-9

E-64d [for Biochemical Research] TCI E1337

E-64d [for Biochemical Research] TCI E1337

Chemical Identity

Other names
E-64d · Loxistatin · Ethyl (2S,3S)-3-[[(2S)-4-Methyl-1-[(3-methylbutyl)amino]-1-oxo-2-pentanyl]carbamoyl]-2-oxiranecarboxylate · (2S,3S)-3-[[(2S)-4-Methyl-1-[(3-methylbutyl)amino]-1-oxo-2-pentanyl]carbamoyl]-2-
CAS No.
88321-09-9
PubChem
CID 65663·SID 468591716
Formula
C17H30N2O5
Molecular weight
342.44 g/mol
Purity
>95.0%(HPLC)
Storage
-20°C
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
ethyl (2S,3S)-3-[[(2S)-4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylate
SMILES
CCOC(=O)C1C(O1)C(=O)NC(CC(C)C)C(=O)NCCC(C)C
InChIKey
SRVFFFJZQVENJC-IHRRRGAJSA-N
MDL
MDL00132883
Rp 2.702.700,00
Rp 1.905.750,00 Rp 2.702.700,00
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E-64d is a chemical compound widely used in biochemical research for its role as a protease inhibitor. This compound plays a crucial part in laboratory experiments aimed at studying enzyme activity and inhibition mechanisms. It is particularly valuable in understanding how enzymes function within biological systems and how their activity can be modulated. Its application extends to various research areas, including molecular interactions and biochemical processes, making it an essential tool for scientists working in biochemistry and pharmacology.

E-64d is preferred due to its chemical stability under specific conditions and its high affinity for certain protease enzymes. These properties allow it to selectively inhibit enzyme activity without interfering with other biological pathways. This selectivity is a key advantage, enabling researchers to conduct precise and targeted studies. The compound's ability to block enzyme activity effectively makes it a reliable choice for experiments requiring controlled inhibition. Its consistent performance and predictable behavior further enhance its appeal in laboratory settings.

In Indonesian laboratories, E-64d is commonly used in scientific research, especially in the fields of biochemistry and pharmacology. Researchers rely on this compound to investigate diseases associated with protease activity, such as neurodegenerative disorders and inflammatory conditions. Its relevance in understanding enzyme mechanisms and their impact on health makes it a valuable resource for both academic and applied research in Indonesia.

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Related TCI products

  • Biochemical Research: E-64d is ideal for studying enzyme inhibition mechanisms, allowing researchers to analyze how protease activity can be selectively blocked.
  • Neurodegenerative Disease Studies: The compound is used to investigate the role of proteases in conditions like Alzheimer’s and Parkinson’s, aiding in drug development.
  • Inflammatory Disease Research: E-64d helps in understanding protease involvement in inflammation, supporting the development of anti-inflammatory therapies.
  • Enzyme Kinetics Analysis: Its high affinity for proteases makes it suitable for experiments measuring enzyme activity and inhibition kinetics.
  • Drug Discovery and Development: E-64d is used to screen potential inhibitors for therapeutic applications, particularly in targeting protease-related diseases.

Brand TCI
CAS number 88321-09-9
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Enzymes, Enzyme Inhibitors, Enzyme Substrates
Pack sizes —
Physical form —
Storage Store in a cool, dry place away from direct light

E-64d should be stored in a cool, dry environment, away from direct sunlight and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent contamination and degradation. Proper labeling of storage containers is essential for safety and traceability. Laboratory personnel should wear appropriate personal protective equipment when handling the compound to minimize exposure. While no specific storage conditions beyond standard chemical handling are required, maintaining a controlled environment ensures the compound remains effective for research purposes. Always follow standard laboratory safety protocols when working with biochemical reagents.

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