Fadrozole Hydrochloride Hemihydrate TCI F1301

Chemical Identity

Other names: 4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile Hydrochloride Hemihydrate
CAS No.: 176702-70-8
PubChem: CID 11954367·SID 468591906
Formula: C14H13N3.HCl.1/2H2O
Molecular weight: 268.75 g/mol
Purity: >98.0%(HPLC)(T)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: bis(4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile);hydrate;dihydrochloride
SMILES: C1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N.C1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N.O.Cl.Cl
InChIKey: RBNOZCGLHXZRLF-UHFFFAOYSA-N

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Fadrozole Hydrochloride Hemihydrate is a chemical compound widely used in biochemical experiments and scientific research. As an enzyme inhibitor, it specifically targets aromatase, an enzyme critical in the conversion of testosterone to estradiol. This makes it a valuable tool in laboratories where precise control over hormonal pathways is essential. Its role extends beyond basic research, supporting advanced studies in endocrinology and pharmacology. Due to its chemical stability and solubility, it is a reliable reagent for various experimental setups.

The compound is known for its high purity, chemical stability, and solubility in organic solvents, which are key factors in its popularity among researchers. These properties ensure consistent performance across different experimental conditions, making it a preferred choice for reproducible results. Its molecular structure allows for effective interaction with aromatase, enhancing the accuracy of enzyme inhibition studies. The solid form of the compound also simplifies handling and storage, contributing to its widespread use in laboratory settings.

In Indonesian laboratories, Fadrozole Hydrochloride Hemihydrate is commonly used in research related to reproductive health, endocrinology, and pharmacology. It plays a crucial role in studies involving hormonal therapy, cancer research, and steroid metabolism analysis. Its application in drug development and medical therapy research further underscores its importance in both academic and applied scientific work.

TCI brochures (PDF)

Antimicrobials and Antitumor Agents for Research and Experimental Use 2025-04-24 · p. 17
Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 17

Related TCI products

Hormonal Therapy Research: This compound is ideal for studying the effects of aromatase inhibition in hormonal treatments, providing insights into endocrine system regulation.
Cancer Research: It is used to investigate the role of aromatase in tumor growth, particularly in hormone-sensitive cancers such as breast cancer.
Steroid Metabolism Analysis: Its ability to inhibit aromatase makes it a key reagent in analyzing steroid conversion pathways and metabolic processes.
Drug Development: It supports the development of pharmaceuticals targeting aromatase, aiding in the creation of more effective hormonal therapies.
Endocrinology Studies: It is widely used in research focused on hormonal imbalances and their impact on physiological functions.

Brand	TCI
CAS number	176702-70-8
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Enzymes, Enzyme Inhibitors, Enzyme Substrates
Pack sizes	Available in various quantities as per standard laboratory requirements
Physical form	Solid hemihydrate
Storage	Store in a cool, dry place away from moisture and direct sunlight

Fadrozole Hydrochloride Hemihydrate should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to keep it in a sealed container to avoid moisture exposure, which can affect its purity and effectiveness. Due to its solid form, it is easy to handle and measure accurately in laboratory settings. General laboratory precautions include avoiding direct contact with skin and eyes, and using appropriate personal protective equipment when handling. It should be stored away from incompatible substances to ensure safety. Proper storage conditions help preserve the compound's integrity and ensure reliable results in experiments.

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