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Description
TCI G0239 L-Gulose is a rare hexose sugar that is seldom encountered in meaningful quantities in nature, which is why it is almost always supplied through chemical synthesis or enzymatic conversion rather than isolation from natural sources. As a member of the aldohexose family, L-gulose shares the same molecular formula as glucose but differs in the configuration of its chiral centres. This subtle difference is precisely what makes it so valuable in the glycoscience laboratory: the compound serves as a tool for testing how strictly an enzyme, lectin, or receptor discriminates between the spatial arrangements of hydroxyl groups on sugar molecules that otherwise appear very similar.
The characteristics that lead researchers to select L-gulose are its rarity and its stereochemical distinctiveness. In plant ascorbic acid biosynthesis, L-gulose is recognised as an intermediate in one of the alternative pathways, making the compound an important material for tracing and providing evidence for that metabolic route. Physically it is a white crystalline solid that dissolves readily in water like other simple sugars, and it can be analysed by chromatography as well as by polarimetry. Its availability in pure form allows the preparation of standard solutions at precisely known concentrations for quantification work.
For laboratories in Indonesia, a rare sugar of this kind is typically used in academic research groups, university glycobiology and biochemistry laboratories, and institutional research centres working on carbohydrate recognition and plant metabolism. Because it is not obtainable in useful amounts from natural material, reliable access to a synthesised, well-characterised grade is essential for reproducible carbohydrate-specificity studies and for building accurate calibration standards for analytical methods.
Laboratory Applications
Enzyme specificity screening — L-gulose acts as a stereochemically distinct probe that reveals how strictly a carbohydrate-active enzyme discriminates between hydroxyl configurations on otherwise closely related hexose substrates.
Lectin and receptor binding studies — because it shares the molecular formula of glucose but differs in chirality, it tests whether a lectin or receptor recognises spatial arrangement rather than composition alone.
Ascorbic acid biosynthesis research — as a known intermediate in an alternative plant pathway, it supports work aimed at tracing and confirming that metabolic route experimentally.
Analytical standard preparation — its availability in pure form allows precise standard solutions to be prepared for quantification by chromatographic methods in carbohydrate analysis.
Polarimetric and chromatographic method development — the compound is amenable to both polarimetry and chromatography, making it useful when establishing or validating separation and detection methods for rare sugars.
Specifications
Brand: TCI
CAS number: 6027-89-0
Category: Chemistry > Chemical Biology > Glycoscience
Pack sizes: supplied in the catalogue pack sizes offered for this item; please confirm the currently available option when ordering
Physical form: white crystalline solid, readily soluble in water
Storage: keep in a tightly closed container in a cool, dry place away from moisture
Handling and Storage
Store the container tightly closed in a cool, dry place, protected from moisture and direct sunlight, since crystalline sugars readily take up atmospheric water and this can affect the accuracy of gravimetric weighing. Use clean, dry glass or chemically compatible plastic containers with well-fitting closures, and reseal immediately after each use. Handle in a well-ventilated area with standard laboratory personal protective equipment, including a laboratory coat, safety glasses, and gloves, and avoid generating dust when weighing the solid. Use dry spatulas to prevent contamination of the stock material, and label any prepared solutions clearly with the concentration and preparation date. Always consult the manufacturer's safety data sheet before first use.
