(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic Acid is a chiral compound widely used in asymmetric synthesis, playing a crucial role in the development of chiral molecules. This optical resolving agent is essential for researchers working in organic chemistry and pharmaceutical sciences, as it enables precise control over stereocenter formation. Its unique structure allows it to act as a chiral building block, facilitating the synthesis of bioactive compounds with specific stereochemistry. In modern laboratories, this compound is a key component in the pursuit of enantiomerically pure substances, which are vital in drug development and advanced chemical research.
The compound's optical activity and high chemical stability make it a preferred choice for synthetic chemists. Its ability to rotate polarized light is a defining feature, allowing for the separation of enantiomers in chiral resolution processes. The presence of the trifluoromethyl group enhances its chemical stability, reducing the risk of unwanted side reactions during synthesis. Additionally, its solubility in organic solvents simplifies handling and integration into complex synthetic pathways. These properties collectively make it a reliable and efficient reagent for laboratory applications requiring precise stereochemical control.
In Indonesian laboratories, this compound is commonly used in research focused on the synthesis of bioactive compounds. It is a valuable tool for academic institutions and research centers working on drug discovery and organic synthesis. Its application in the development of pharmaceuticals and fine chemicals underscores its importance in both academic and industrial research settings. The compound's versatility and reliability have made it a standard in many laboratory workflows across Indonesia.
- Asymmetric Synthesis: This compound is ideal for chiral synthesis due to its optical activity, enabling the creation of enantiomerically pure compounds essential in pharmaceutical development.
- Chiral Resolution: Its optical resolving properties make it suitable for separating enantiomers, a critical process in the production of high-purity pharmaceuticals.
- Organic Chemistry Research: It serves as a chiral building block, allowing researchers to construct complex molecules with specific stereochemistry.
- Bioactive Compound Development: Its use in synthesizing bioactive molecules supports research in drug discovery and medicinal chemistry.
- Academic and Industrial Research: Widely adopted in Indonesian laboratories, it supports both academic studies and industrial applications in chemical synthesis.
| Brand | TCI |
|---|---|
| CAS number | 20445-31-2 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Asymmetric Synthesis > Chiral Building Blocks |
| Pack sizes | Available in various quantities as per supplier specifications |
| Physical form | Solid, crystalline appearance |
| Storage | Store in a cool, dry place away from light and moisture |
This compound should be stored in a cool, dry environment, away from direct sunlight and moisture. It is recommended to keep it in a sealed container to prevent exposure to air and humidity. Due to its chemical stability, it does not require refrigeration, but long-term storage should be in a controlled room temperature setting. Laboratory personnel should handle it with care, using appropriate personal protective equipment when necessary. It is not classified as hazardous under standard laboratory conditions, but standard safety protocols should be followed to ensure safe handling and storage.
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