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Description
2-Methylquinoline N-Oxide is a heterocyclic organic compound belonging to the quinoline N-oxide family, widely employed as a building block in organic synthesis within the chemistry laboratory. It serves as an important starting material for constructing substituted quinoline structures and for investigating oxidation, substitution, and functional-group transformation reactions on the heterocyclic ring. Because the quinoline framework is frequently encountered in biologically active compounds, this reagent is commonly used in research aimed at developing pharmaceutical candidates, agrochemicals, and functional materials. The product is supplied under CAS number 1076-28-4 and is available in 1 g and 5 g pack sizes.
The main advantage of this compound lies in its N-oxide group, which makes positions on the quinoline ring more reactive and readily susceptible to regioselective reactions, allowing chemists to introduce substituents at well-defined sites. The N-oxide functionality also improves the solubility of the compound in polar solvents, which simplifies handling and facilitates purification and analytical steps during synthesis. As a product of TCI, this material is provided with consistent quality standards, making it well suited to research that demands reproducible results across repeated experiments.
In Indonesian laboratories, this reagent is typically applied in synthetic chemistry research at universities, research institutes, and industry R&D facilities, where it supports studies on heterocyclic chemistry and the preparation of quinoline-based intermediates. It is a practical choice for graduate research projects and method development involving oxidation and functional-group manipulation, as well as for small-scale screening of reaction conditions before scale-up. Researchers appreciate its reliable availability in convenient 1 g and 5 g pack sizes, which allows laboratories to purchase quantities appropriate to their experimental needs.
Laboratory Applications
Synthesis of substituted quinolines: As a versatile building block, this N-oxide enables regioselective introduction of substituents onto the quinoline ring, making it ideal for constructing diverse quinoline derivatives in one step.
Oxidation chemistry studies: The N-oxide group participates in oxidation and oxygen-transfer reactions, so the compound serves as a useful model substrate for investigating oxidation pathways and reaction mechanisms.
Pharmaceutical research: The quinoline scaffold appears in many biologically active molecules, so this building block supports medicinal chemistry projects aimed at preparing quinoline-based drug candidates and structural analogs.
Agrochemical development: Quinoline derivatives are widespread in agrochemical structures, and this reagent provides a convenient starting point for synthesizing intermediates used in the development of crop-protection compounds.
Functional materials and analytical studies: Improved solubility in polar solvents makes this compound easier to purify and analyze, supporting research on quinoline-based functional materials and analytical method development.
Specifications
Brand: TCI
Product: 2-Methylquinoline N-Oxide (TCI M3000)
CAS number: 1076-28-4
Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
Available pack sizes: 1 g and 5 g
Storage: keep in a cool, dry place away from direct sunlight and sources of heat
Handling and Storage
Store the product in its original, tightly sealed container in a cool, dry, and well-ventilated area away from direct sunlight and sources of heat. Keep the container closed when not in use to protect the compound from moisture and contamination. Use appropriate personal protective equipment, including laboratory gloves, safety goggles, and a lab coat, when handling the material. Work in a fume hood or well-ventilated area to avoid inhaling dust or vapors. Avoid contact with skin and eyes, and wash hands thoroughly after handling. Keep the material away from incompatible substances and open flames, and follow standard laboratory waste disposal procedures.
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