N-Methyl-7H-purin-6-amine TCI M3166

Chemical Identity

CAS No.: 443-72-1
PubChem: CID 67955·SID 468592307
Formula: C6H7N5
Molecular weight: 149.15 g/mol
Purity: >98.0%(HPLC)(T)
Reference databases: ChEBI·ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: N-methyl-7H-purin-6-amine
SMILES: CNC1=NC=NC2=C1NC=N2
InChIKey: CKOMXBHMKXXTNW-UHFFFAOYSA-N

Rp 3.180.450,00

Sale Sold out

Shipping calculated at checkout.

Berat 1g

Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 2-4 minggu setelah pembayaran.

Dokumen Keamanan & Mutu

↓ Unduh SDS / MSDS (PDF resmi TCI)

CoA (Certificate of Analysis)

Spesifik per batch produksi — diterbitkan dan dikirim bersama barang sesuai nomor lot yang Anda terima.

Contoh CoA segera tersedia.

💬 Minta CoA via WhatsApp

View full details

N-Methyl-7H-purin-6-amine, identified by CAS number 443-72-1, is a purine derivative methylated at the amino group in the 6-position, more widely known among researchers as N6-methyladenine. The compound is a heterocyclic building block that retains an intact purine skeleton, meaning it shares the same core structure as the nitrogenous bases that make up nucleic acids. For this reason, its presence in the laboratory is not limited to its role as a synthetic starting material; it also serves as an important reference molecule in studies of nucleobase modification and in the rapidly expanding field of epigenetics research.

The characteristics that make this material a frequent choice are its nitrogen-rich purine ring system combined with its ability to form hydrogen bonds in a directed manner. The methyl group on the exocyclic nitrogen alters the hydrogen bond donor and acceptor pattern relative to ordinary adenine, which makes it an appropriate model for examining how methylation influences molecular recognition. The purine framework additionally provides several positions that can be modified further through alkylation, glycosylation, or coupling reactions, giving considerable freedom to researchers who are constructing nucleoside analogues and purine-based enzyme inhibitor compounds.

In Indonesian laboratories, this building block is typically encountered in university and institutional research settings where organic synthesis, medicinal chemistry, and molecular biology programmes overlap. It is used in small-scale exploratory syntheses, in the preparation of modified nucleoside analogues, and as a reference compound when analytical methods for methylated nucleobases are being developed or validated. Its role as a recognised marker in epigenetics work also makes it relevant to groups studying nucleic acid modification.

Related TCI products

Epigenetics research — as N6-methyladenine, the compound is a recognised reference molecule for investigating how methylation of adenine affects nucleic acid function and molecular recognition patterns.
Nucleoside analogue synthesis — the intact purine skeleton offers several modifiable positions for glycosylation and coupling reactions, allowing researchers to build modified nucleoside structures from a well-defined starting point.
Medicinal chemistry and inhibitor development — the purine framework is a common scaffold in purine-based enzyme inhibitors, and this building block provides a methylated entry point for such synthetic programmes.
Hydrogen bonding and molecular recognition studies — the methyl group on the exocyclic nitrogen changes the donor and acceptor pattern relative to adenine, making it a suitable model system for binding studies.
Analytical method development — the compound serves as a defined reference material when chromatographic or spectroscopic methods for detecting methylated nucleobases are being established or validated in the laboratory.

Brand	TCI
CAS number	443-72-1
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes	available in standard research-scale packaging; please confirm the packaging option when ordering
Physical form	—
Storage	store in a cool, dry place in a tightly closed original container

Product code: M3166
Chemical name: N-Methyl-7H-purin-6-amine (N6-methyladenine)

Store the container tightly closed in a cool, dry, well-ventilated area, away from direct sunlight, moisture, and incompatible chemicals. The original manufacturer packaging is the most suitable container for long-term storage; if transferred, use clean and chemically compatible glass or plastic vessels that are clearly labelled with the compound name and CAS number. Handle the solid in a fume hood or a well-ventilated workspace, and wear standard personal protective equipment including safety goggles, a laboratory coat, and suitable gloves. Avoid generating dust during weighing and transfer. Always consult the manufacturer's safety data sheet before use, and dispose of residues and contaminated materials according to institutional chemical waste procedures.

—