Olmesartan TCI O0507

Chemical Identity

CAS No.: 144689-24-7
PubChem: CID 158781·SID 354335584
Formula: C24H26N6O3
Molecular weight: 446.5 g/mol
Purity: >98.0%(HPLC)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
SMILES: CCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)C(C)(C)O
InChIKey: VTRAEEWXHOVJFV-UHFFFAOYSA-N

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Olmesartan is a chemical compound widely used in pharmaceutical research and laboratory experiments. As a member of the angiotensin-converting enzyme (ACE) inhibitor family, it plays a crucial role in lowering blood pressure by inhibiting the production of angiotensin II, a key factor in blood vessel constriction. This compound is essential for studying hypertension, pharmacological effects of drugs, and the mechanisms of drug action. Its presence in experimental settings allows researchers to explore the physiological and biochemical responses associated with cardiovascular health.

Olmesartan is favored for its chemical stability and predictable behavior under various experimental conditions. It maintains its structural integrity and physical consistency, making it reliable for use in analytical and biochemical methods. Its stability ensures that results from experiments remain consistent and reproducible, which is vital for scientific research. The compound’s well-defined molecular structure and reliable performance make it a trusted choice for laboratories requiring accurate and dependable reagents.

In Indonesian laboratories, olmesartan is commonly used in clinical research, drug development, and pharmacological side effect studies. It is also applied in research focused on preventing heart disease and stroke, which are significant public health concerns in the region. Its versatility and reliability make it an essential component in various scientific investigations aimed at improving healthcare outcomes.

TCI brochures (PDF)

Pharmacologically Active Metabolites 2025-07-22 · p. 2
Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 21

Related TCI products

Clinical research applications benefit from olmesartan's role in studying hypertension and cardiovascular disease, offering insights into drug efficacy and patient responses.
Drug development projects utilize olmesartan to evaluate pharmacological mechanisms and potential therapeutic applications in treating hypertension.
Pharmacological side effect studies rely on olmesartan to analyze the safety and adverse effects of ACE inhibitors in experimental models.
Cardiovascular disease prevention research employs olmesartan to investigate its impact on reducing the risk of heart disease and stroke.
Biomedical research uses olmesartan to explore molecular pathways involved in blood pressure regulation and vascular function.

From the TCI brochure

A Selective AT1 Subtype Angiotensin II Receptor Antagonist

Brand	TCI
CAS number	144689-24-7
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents
Pack sizes	Available in various quantities as per standard laboratory requirements
Physical form	Solid
Storage	Store in a cool, dry place away from direct light

Olmesartan should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to keep the compound in a tightly sealed container to minimize exposure to moisture and air. Laboratory personnel should handle olmesartan with care, using appropriate personal protective equipment such as gloves and safety goggles. The substance is generally stable under normal laboratory conditions, but it should be stored away from incompatible materials to ensure safety. Proper labeling and storage practices are essential to maintain the integrity of the compound and ensure safe handling in research settings.

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