Polyvinylpyrrolidone K 15 (PVP K 15) is a versatile chemical compound widely used in pharmaceutical research and drug development. It is a polymer with an average molecular weight of approximately 10,000, making it a key component in various drug delivery systems. In the laboratory, PVP K 15 plays a crucial role in formulating stable and effective drug products, particularly in controlled release systems. Its ability to enhance the solubility and stability of active pharmaceutical ingredients makes it an essential reagent for researchers aiming to develop new therapeutic solutions. This material is commonly utilized in both academic and industrial settings to support the advancement of drug formulation technologies.
PVP K 15 is preferred due to its excellent physical and chemical properties, including high hydrophilicity and compatibility with a wide range of substances. It is non-toxic and has good biocompatibility, which makes it safe for use in pharmaceutical applications. The polymer’s ability to bind with various active molecules enhances the efficiency and safety of drug delivery systems. Additionally, its capacity to absorb water and form stable aqueous solutions makes it ideal for use in suspensions, emulsions, and tablet formulations. These characteristics contribute to its widespread adoption in both research and development environments.
In Indonesian laboratories, PVP K 15 is commonly used in pharmaceutical development projects, particularly in the formulation of controlled-release and sustained-release drug products. It is also utilized in the preparation of suspensions and emulsions, where its hydrophilic nature ensures stability and uniformity. Its non-toxic profile and compatibility with various excipients make it a reliable choice for researchers in Indonesia working on drug delivery systems and formulation development.
- Drug Delivery System Development: PVP K 15 is ideal for creating controlled-release formulations due to its ability to enhance drug solubility and stability.
- Suspension and Emulsion Formulation: Its high hydrophilicity allows it to absorb water and form stable aqueous solutions, making it suitable for suspensions and emulsions.
- Tablet Formulation: PVP K 15 is used as a binder and disintegrant in tablet manufacturing, improving the cohesion and disintegration of the final product.
- Active Pharmaceutical Ingredient (API) Stabilization: The polymer's compatibility with various substances helps in stabilizing APIs during formulation and storage.
- Research in Pharmaceutical Development: Its non-toxic and biocompatible nature makes it a preferred choice for laboratory research involving drug delivery and formulation studies.
| Brand | TCI |
|---|---|
| CAS number | 9003-39-8 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Pharmaceutical Development and Drug Discovery Research Reagents > Drug Delivery Systems (DDS) |
| Pack sizes | Available in various quantities as per supplier specifications |
| Physical form | Powder |
| Storage | Store in a cool, dry place away from direct sunlight |
PVP K 15 should be stored in a cool, dry place, away from direct sunlight and moisture to maintain its chemical integrity. It is recommended to use airtight containers to prevent exposure to humidity, which could affect its stability. As a powder, it should be handled with care to avoid inhalation or skin contact. In laboratory settings, it is important to ensure proper ventilation when working with this material. Due to its non-toxic nature, it is generally safe to handle, but standard laboratory safety protocols should still be followed. The material should not be stored near incompatible substances or in areas with high temperature fluctuations. Proper labeling of storage containers is essential to ensure safe handling and prevent accidental misuse.
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