Ethyl Undecafluoroamyl Ketone from TCI is a fluorinated ketone. One side of its carbonyl group carries an ordinary ethyl group, and the other side carries a perfluoropentyl chain containing eleven fluorine atoms. This asymmetric structure puts a hydrocarbon segment and a perfluorinated segment in one small molecule. In the laboratory, chemists use it as a fluorinated building block to add perfluoroalkyl segments to target molecules. It is used mainly in functional materials research, medicinal chemistry, and studies of fluorine-activated carbonyl reactivity.
The perfluoroalkyl chain is strongly electron-withdrawing, so the carbonyl carbon in this ketone is much more electrophilic than in ordinary aliphatic ketones. As a result, the compound reacts more readily with nucleophiles and tends to form hydrates or hemiketals in the presence of water or alcohols. The perfluorinated segment is both hydrophobic and lipophobic, and it gives the fluorinated part of the molecule high chemical and thermal stability. Researchers choose this compound because it combines a highly reactive carbonyl group with a chemically inert fluorinated chain.
In Indonesia, research on organofluorine compounds continues to grow in organic chemistry, pharmaceutical, and materials science laboratories at universities, research institutes, and industrial R&D centres. Researchers there use fluorinated building blocks like this ketone to design new molecules, to study how fluorination changes reactivity and physical behaviour, and to prepare model compounds for teaching and advanced research. Because it comes from TCI, Indonesian laboratories can expect consistent product identity from one batch to the next, which helps keep synthetic and analytical work reproducible.
- Introducing perfluoroalkyl segments: the compound carries a perfluoropentyl chain with eleven fluorine atoms, so chemists can use it to add a defined fluorinated segment to target molecules during synthesis.
- Studies of activated carbonyl reactivity: the strongly electron-withdrawing perfluoroalkyl chain makes the carbonyl carbon highly electrophilic, so this ketone works well as a model substrate for nucleophilic addition studies.
- Hydrate and hemiketal formation research: the compound readily forms hydrates or hemiketals with water or alcohols, so it suits experiments on equilibrium and stability in activated fluorinated ketones.
- Medicinal chemistry exploration: fluorinated fragments can change the properties of drug candidates, and this building block lets researchers explore perfluoroalkyl substitution in early synthetic and structure–activity studies.
- Functional materials development: the perfluorinated segment is both hydrophobic and lipophobic and has high chemical and thermal stability, which makes the compound relevant for designing fluorinated materials and surface-active molecules.
| Brand | TCI (product code P1363) |
|---|---|
| CAS number | 383177-55-7 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Fluorinated Building Blocks |
| Pack sizes | as listed in the TCI catalogue; please confirm available pack sizes when you order |
| Physical form | refer to the TCI product documentation and Certificate of Analysis |
| Storage | follow the conditions stated on the TCI label and Safety Data Sheet (SDS) |
Store Ethyl Undecafluoroamyl Ketone in its original, tightly closed container, in a cool, dry, well-ventilated area away from heat sources and incompatible materials. The carbonyl group readily forms hydrates and hemiketals, so protect the compound from moisture and close the container straight after each use. Handle it in a fume hood and wear suitable gloves, safety glasses, and a lab coat. Read the TCI Safety Data Sheet (SDS) before use, and dispose of fluorinated waste according to your institution's procedures and local regulations.
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