Phentolamine Mesylate TCI P1985

Chemical Identity

CAS No.: 65-28-1
PubChem: CID 91430·SID 135727347
Formula: C18H23N3O4S
Molecular weight: 377.5 g/mol
Purity: >98.0%(HPLC)(T)
Reference databases: ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid
SMILES: CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.CS(=O)(=O)O
InChIKey: OGIYDFVHFQEFKQ-UHFFFAOYSA-N

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Phentolamine Mesylate is a chemical compound widely used in pharmacological and biochemical research. As an alpha-adrenergic antagonist, it plays a crucial role in inhibiting the effects of the neurotransmitter norepinephrine. This makes it an essential reagent for experiments related to the sympathetic nervous system. Its ability to block alpha-adrenergic receptors allows researchers to study the physiological and pharmacological responses of various tissues and systems. In laboratory settings, it is a key component in understanding the mechanisms of drug action and the body’s response to different stimuli.

The compound is valued for its chemical stability under controlled conditions, which ensures consistent performance in experimental setups. Its specific molecular structure allows for predictable reactivity in a variety of chemical reactions and assays. Additionally, its solid form facilitates accurate weighing and easy handling in different research scales. These properties make it a reliable choice for both small-scale and large-scale experiments, ensuring reproducibility and precision in research outcomes.

In Indonesian laboratories, Phentolamine Mesylate is commonly used in studies related to blood pressure regulation, vascular responses, and drug interactions. Its role in pharmacological testing is vital for assessing the efficacy and safety of new compounds. Due to its specificity and reliability, it is a preferred reagent for applications requiring high accuracy and controlled experimental conditions.

TCI brochures (PDF)

Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 21

Related TCI products

Pharmacological research for studying alpha-adrenergic receptor antagonism and drug interactions.
Vascular physiology studies to analyze blood pressure regulation and vasoactive responses.
Drug development experiments to evaluate the efficacy and mechanism of action of new pharmaceutical compounds.
Neuropharmacological investigations into the effects of neurotransmitters on the sympathetic nervous system.
Biochemical assays requiring a stable and reactive compound for controlled experimental conditions.

Brand	TCI
CAS number	65-28-1
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents
Pack sizes	Available in various quantities as per standard laboratory supply
Physical form	Solid
Storage	Store in a cool, dry place away from direct sunlight

Phentolamine Mesylate should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep the compound in a tightly sealed container to prevent moisture absorption and contamination. Due to its reactivity, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. Avoid exposure to heat or direct light to preserve its integrity. In laboratory settings, it should be stored separately from incompatible substances to ensure safety. Proper labeling and storage conditions are essential to maintain its effectiveness and ensure safe handling during experiments.

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