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TCI

CAS 80621-81-4

Rifaximin TCI R0101

Rifaximin TCI R0101

Chemical Identity

CAS No.
80621-81-4
PubChem
CID 72698618·SID 172089119
Formula
C43H51N3O11
Molecular weight
785.9 g/mol
Purity
>97.0%(HPLC)(N)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21E)-2,15,17,36-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22,30-octamethyl-6,23-dioxo-8,37-dioxa-24,27,33-triazahexacyclo[23.10.1.14,7.05,35.026,34.027,32]heptatriaconta-1(35),2,4,9,19,21,25(36),26(34),28,30,32-un
SMILES
C[C@H]1/C=C/C=C(/C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)O[C@@](C4=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C5=C2N6C=CC(=CC6=N5)C)O)\C
InChIKey
NZCRJKRKKOLAOJ-KOPWYESNSA-N
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Rifaximin is an antibiotic widely used in biochemical experiments and microbiological research. As an active compound within the rifamycin family, it functions by inhibiting bacterial RNA synthesis through the binding of RNA polymerase. This mechanism makes it a valuable tool for researchers aiming to control microbial growth or study antibiotic resistance. Its versatility allows it to be applied in various experimental setups, from bacterial culture media to pharmacological studies. Rifaximin is particularly useful in scenarios where precise control over microbial populations is required.

Rifaximin is favored for its stability under certain conditions and its resistance to chemical degradation. These properties make it suitable for use in laboratory procedures that involve exposure to harsh chemical environments. Additionally, its non-irritating nature ensures safety during chemical manipulations, reducing the risk of adverse reactions. This combination of chemical stability and safety makes Rifaximin a reliable choice for both routine and specialized laboratory applications.

In Indonesian laboratories, Rifaximin is commonly used in pharmaceutical, microbiological, and bioinformatics research. Its role in bacterial inhibition and sensitivity testing makes it a preferred material for researchers working on antibiotic development and microbial analysis. Its consistent performance and reliability have made it a staple in many research settings across Indonesia.

  • Microbial Culture Studies: Rifaximin is used to control bacterial growth in culture media, allowing researchers to study microbial behavior under controlled conditions.
  • Antibiotic Sensitivity Testing: It serves as a standard antibiotic for determining the susceptibility of bacterial strains to various antimicrobial agents.
  • Pharmacological Research: Rifaximin is employed in experiments to assess the effects of antibiotics on cellular processes and bacterial metabolism.
  • Biochemical Assays: Its ability to inhibit RNA synthesis makes it useful in assays that require the modulation of bacterial gene expression.
  • Environmental Microbiology: It is used to study the impact of antibiotics on microbial communities in environmental samples.

Brand TCI
CAS number 80621-81-4
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Antibiotics
Pack sizes Available in standard laboratory quantities
Physical form Powder
Storage Store in a cool, dry place away from light

Rifaximin should be stored in a cool, dry place, away from direct sunlight and moisture to maintain its stability and effectiveness. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its chemical stability, it is less prone to degradation, but proper storage is essential to preserve its potency. Laboratory personnel should handle Rifaximin with care, using appropriate personal protective equipment when necessary. It is important to ensure that the storage area is secure and accessible only to authorized individuals to prevent accidental exposure or misuse. Regular monitoring of storage conditions can help maintain the integrity of the compound throughout its shelf life.

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