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TCI

CAS 122320-73-4

Rosiglitazone TCI R0106

Rosiglitazone TCI R0106

Chemical Identity

CAS No.
122320-73-4
PubChem
CID 77999·SID 253659589
Formula
C18H19N3O3S
Molecular weight
357.4 g/mol
Purity
>98.0%(HPLC)(T)
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
SMILES
CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3
InChIKey
YASAKCUCGLMORW-UHFFFAOYSA-N
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Rosiglitazone is a chemical compound widely used in pharmacological and biochemical research to study the mechanisms of action of hypoglycemic drugs in patients with diabetes mellitus. As a key reagent in experimental settings, it plays a vital role in laboratory investigations focused on the activation of PPAR-γ, a receptor involved in the regulation of glucose and lipid metabolism. This compound is essential for understanding how certain drugs affect cellular responses and metabolic pathways. Its application extends to both clinical and laboratory research, making it a critical component in drug development and therapeutic evaluation.

Rosiglitazone is chemically stable and soluble in organic solvents such as ethyl acetate and acetone, which makes it highly versatile for use in various analytical methods. These properties allow it to be effectively employed in techniques like spectroscopy, chromatography, and chemical reactions. Its clarity and distinct chemical structure further enhance its utility in experiments requiring precision and accuracy. The availability in multiple packaging formats ensures that researchers can easily adapt its use to meet the specific needs of their experiments.

In Indonesian laboratories, Rosiglitazone is commonly used in pharmacological research, particularly in studies related to diabetes treatment and metabolic disorders. Its role in experimental drug testing and the evaluation of therapeutic efficacy makes it a preferred choice for researchers working in both academic and industrial settings. Its consistent performance and reliability contribute to the quality and reproducibility of scientific findings in the region.

  • Pharmacological research for studying the mechanism of action of hypoglycemic drugs in diabetes treatment.
  • Biochemical experiments focused on PPAR-γ activation and its impact on glucose and lipid metabolism.
  • Drug development studies to evaluate the efficacy and cellular response to therapeutic agents.
  • Analytical chemistry applications in spectroscopy and chromatography for compound identification and quantification.
  • Metabolic disorder research to investigate the role of PPAR-γ in metabolic regulation and disease progression.

Brand TCI
CAS number 122320-73-4
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents
Pack sizes Available in various packaging formats for experimental use
Physical form —
Storage Store in a cool, dry place away from light

Rosiglitazone should be stored in a cool, dry place away from direct light to maintain its chemical stability and prevent degradation. It is recommended to use airtight containers to minimize exposure to moisture and contaminants. In laboratory settings, proper labeling and safe handling procedures are essential to ensure the integrity of the compound during storage and use. Researchers should avoid contact with skin and eyes, and appropriate personal protective equipment should be worn when handling the material. Regular monitoring of storage conditions is advised to ensure the material remains suitable for experimental applications.

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