(R)-(-)-Rolipram TCI R0182

Chemical Identity

CAS No.: 85416-75-7
PubChem: CID 448055·SID 354333406
Formula: C16H21NO3
Molecular weight: 275.34 g/mol
Purity: >98.0%(HPLC)
Reference databases: ChEBI·ChemSpider

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (4R)-4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one
SMILES: COC1=C(C=C(C=C1)[C@H]2CC(=O)NC2)OC3CCCC3
InChIKey: HJORMJIFDVBMOB-LBPRGKRZSA-N

Rp 13.911.450,00

~~Rp 9.744.000,00~~ Rp 13.911.450,00

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(R)-(-)-Rolipram is a chemical compound widely used in life science research, particularly in biochemical and reagent applications. It functions as an inhibitor of phospholipase A2, an enzyme central to inflammatory processes and immune responses. This compound plays a crucial role in understanding biological mechanisms related to inflammation, neurodegenerative diseases, and pharmacological effects on the nervous system. Its presence in laboratory settings enables researchers to explore complex biochemical pathways and develop targeted therapeutic strategies.

The high purity and chemical stability of (R)-(-)-Rolipram make it a preferred choice for scientific experiments requiring accuracy and consistency. Its molecular structure is highly specific, allowing it to interact selectively with biological targets. This specificity is essential for studies aiming to isolate and analyze particular biochemical reactions without interference from other compounds. Additionally, its consistent performance across multiple experiments ensures reliable and reproducible results, which are fundamental to scientific research.

In Indonesian laboratories, (R)-(-)-Rolipram is commonly used in academic and industrial research settings. It supports studies in pharmacology, biochemistry, and molecular biology, particularly in institutions focused on drug development and disease mechanisms. Its application aligns with the growing demand for high-quality reagents in scientific research, making it a valuable resource for researchers in Indonesia.

TCI brochures (PDF)

Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 30

Related TCI products

Inflammation Research – (R)-(-)-Rolipram is ideal for studying inflammatory pathways due to its inhibitory effect on phospholipase A2, which is central to the inflammatory response.
Neurodegenerative Disease Studies – Its ability to modulate enzyme activity makes it useful in investigating the biochemical mechanisms underlying neurodegenerative conditions.
Pharmacological Testing – The compound is used to assess the pharmacological effects of drugs on the nervous system and inflammatory processes.
Enzyme Inhibition Studies – Its specificity for phospholipase A2 makes it a valuable tool in studying enzyme inhibition and enzyme-substrate interactions.
Drug Development – Researchers utilize (R)-(-)-Rolipram to evaluate potential therapeutic agents and their mechanisms of action in preclinical studies.

Brand	TCI
CAS number	85416-75-7
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Enzymes, Enzyme Inhibitors, Enzyme Substrates
Pack sizes	Available in various quantities as per supplier specifications
Physical form	Solid (as per standard product description)
Storage	Store in a cool, dry place away from light

(R)-(-)-Rolipram should be stored in a cool, dry environment, away from direct sunlight and sources of heat. It is recommended to keep the compound in a sealed container to prevent moisture absorption and contamination. Due to its chemical stability, it does not require refrigeration under normal conditions. However, it is important to handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. In laboratory settings, it should be stored separately from incompatible substances to ensure safety. Proper labeling and storage practices help maintain the integrity and effectiveness of the compound during experimental use.

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