Sulfamethoxazole TCI S0361

Chemical Identity

CAS No.: 723-46-6
PubChem: CID 5329·SID 87575873
Formula: C10H11N3O3S
Molecular weight: 253.28 g/mol
Purity: >98.0%(HPLC)(T)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
SMILES: CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N
InChIKey: JLKIGFTWXXRPMT-UHFFFAOYSA-N

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Sulfamethoxazole is a synthetic antibiotic widely used in life sciences and pharmacology research. As a key component in antimicrobial studies, it plays a vital role in inhibiting the growth of bacteria that produce dihydrofolate reductase enzymes. Its chemical structure enables it to act as a competitive inhibitor, making it essential for understanding bacterial metabolism and resistance mechanisms. In laboratory settings, sulfamethoxazole is a fundamental reagent for various biochemical and pharmacological experiments.

The chemical properties of sulfamethoxazole make it a preferred choice for researchers. It exhibits stability under normal laboratory conditions and is soluble in organic solvents such as ethyl acetate and acetone. The presence of a sulfonamide group in its molecular structure contributes to its high affinity for specific target enzymes, enhancing its effectiveness in targeted applications. These characteristics ensure its reliability in both qualitative and quantitative analyses.

In Indonesian laboratories, sulfamethoxazole is commonly used in public health, pharmacology, and microbiology research. It is an essential component in the development of antibiotics and is used to study the efficacy of drugs against respiratory and urinary tract infections. Its role in research and development continues to be critical for advancing medical and scientific knowledge in the region.

TCI brochures (PDF)

Immunology Research Reagents 2026-06-03 · p. 10
Antimicrobials and Antitumor Agents for Research and Experimental Use 2025-04-24 · p. 6
Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 6

Related TCI products

Antimicrobial Activity Testing: Sulfamethoxazole is used to evaluate the effectiveness of antibiotics against specific bacterial strains, aiding in the development of new therapeutic agents.
Drug Concentration Analysis: It serves as a standard for measuring drug levels in biological samples, supporting pharmacokinetic and pharmacodynamic studies.
Enzyme Inhibition Studies: Its ability to inhibit dihydrofolate reductase makes it ideal for investigating enzyme function and bacterial resistance mechanisms.
Chemical Synthesis Reactions: It is a key reagent in the synthesis of other compounds, particularly in organic chemistry and pharmaceutical research.
Microbial Culture Media Preparation: It is incorporated into growth media to study bacterial behavior and response to antimicrobial agents.

Brand	TCI
CAS number	723-46-6
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Antibiotics
Pack sizes	Available in various quantities as per standard laboratory requirements
Physical form	White crystalline powder
Storage	Store in a cool, dry place away from direct sunlight

Sulfamethoxazole should be stored in a cool, dry environment, away from direct sunlight and moisture. It is recommended to use airtight containers to prevent contamination and maintain its chemical integrity. Due to its chemical nature, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. It is not flammable but may cause irritation if inhaled or contacted with skin. Proper labeling and storage conditions ensure its effectiveness and safety in laboratory settings. Always follow standard laboratory safety protocols when working with this compound.

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