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TCI

CAS 141-90-2

2-Thiouracil TCI T0224

2-Thiouracil TCI T0224

Chemical Identity

CAS No.
141-90-2
PubChem
CID 1269845·SID 87576213
Formula
C4H4N2OS
Molecular weight
128.15 g/mol
Purity
>98.0%(HPLC)(T)
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
2-sulfanylidene-1H-pyrimidin-4-one
SMILES
C1=CNC(=S)NC1=O
InChIKey
ZEMGGZBWXRYJHK-UHFFFAOYSA-N
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2-Thiouracil is a chemical compound widely used in biochemical and biomedical experiments. As a derivative of uracil, one of the key components of nucleic acids like RNA, it plays a crucial role in various scientific investigations. In the laboratory, it serves as a building block for the synthesis of compounds with specific biological activities. Its unique chemical structure, where a sulfur atom replaces an oxygen atom in the second position of uracil, gives it distinct reactivity and functionality. This makes it an essential reagent in research focused on nucleotide metabolism and drug development.

The stability and controlled reactivity of 2-Thiouracil make it a preferred choice for researchers. Its high purity and consistent quality ensure reliable results in experiments that demand precision. The compound’s ability to form bonds with various molecules enhances its versatility in different applications. These properties make it suitable for advanced studies in biochemistry and molecular biology. Its chemical stability also allows for long-term storage and use in multiple experimental setups without compromising its integrity.

In Indonesian laboratories, 2-Thiouracil is extensively used in biomedical, pharmacological, and biotechnological research. It is a key component in experiments involving the synthesis of active compounds and the study of nucleotide-related processes. Many research institutions and universities rely on this compound for its reliability and effectiveness in various scientific applications. Its widespread use underscores its importance in modern laboratory practices in Indonesia.

  • Biochemical Synthesis: 2-Thiouracil is used in the synthesis of nucleotide derivatives and other bioactive compounds due to its unique sulfur-containing structure.
  • Drug Development: It is a valuable reagent in the development of pharmaceuticals, particularly in the study of nucleotide-based therapies and metabolic pathways.
  • Nucleotide Metabolism Research: Its role as a nucleotide analog makes it essential for studying metabolic processes and enzyme interactions in nucleic acid metabolism.
  • Molecular Biology Studies: It is frequently used in molecular biology experiments to investigate DNA and RNA interactions and modifications.
  • Biotechnology Applications: It supports biotechnological research by enabling the creation of modified nucleic acids for various genetic and biochemical applications.

Brand TCI
CAS number 141-90-2
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Nucleosides, Nucleotides, Oligonucleotides
Pack sizes Available in various quantities as per standard laboratory requirements
Physical form Solid powder
Storage Store in a cool, dry place away from light and moisture

2-Thiouracil should be stored in a cool, dry environment, away from direct sunlight and moisture. It is recommended to keep it in a sealed container to prevent exposure to air and humidity. Due to its chemical nature, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. It is important to ensure that the storage area is well-ventilated to avoid any potential accumulation of airborne particles. Regular inspection of the container and storage conditions is advised to maintain the compound’s integrity and safety in the laboratory.

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