D-(-)-Luciferin [Chemiluminescence Reagent] TCI A5030

Chemical Identity

CAS No.: 2591-17-5
PubChem: CID 92934·SID 87561286
Formula: C11H8N2O3S2
Molecular weight: 280.3 g/mol
Purity: >98.0%(HPLC)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid
SMILES: C1[C@@H](N=C(S1)C2=NC3=C(S2)C=C(C=C3)O)C(=O)O
InChIKey: BJGNCJDXODQBOB-SSDOTTSWSA-N

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D-(-)-Luciferin is a chemical compound used as a reagent in chemiluminescent reactions, a method of analysis that relies on the emission of light resulting from a chemical reaction. This material plays a crucial role in laboratories where sensitive detection and quantification of biological substances are required. It is commonly utilized in research related to enzymes and their substrates, enabling scientists to measure light output from enzymatic reactions with high precision. Its application spans across various scientific fields, making it an essential tool for analytical processes that demand accuracy and sensitivity.

D-(-)-Luciferin is preferred due to its chemical stability under specific conditions and its ability to react efficiently with luciferase enzymes. These properties make it ideal for applications requiring consistent and reliable results. Its solid form allows for easy handling and storage, while its reactivity ensures that it performs effectively in experimental setups. Additionally, its sensitivity to oxidation and light necessitates careful handling, which further underscores its importance in maintaining the integrity of experimental outcomes.

In Indonesian laboratories, D-(-)-Luciferin is widely used in biomedical, environmental, and pharmaceutical research. It supports the detection of biological compounds, microbial analysis, and the study of enzymatic activity. Its versatility and reliability make it a valuable resource for researchers aiming to achieve accurate and reproducible results in their experiments.

Advantages (TCI brochure)

Reacts with ATP in presence of luciferase and magnesium ion to give oxyluciferin
Emits light at 562 nm

TCI brochures (PDF)

Chemiluminescence Reagents 2025-01-23 · p. 3
Cell Imaging Reagents 2026-06-25 · p. 3
Substrates for Biochemical Assays 2025-04-25 · p. 6
Cancer Research Reagents 2025-04-01 · p. 6
Reagents for Biological Research 2025-03-11 · p. 8

Related TCI products

Biomedical research utilizes D-(-)-Luciferin to detect and quantify biological compounds through chemiluminescent assays, offering high sensitivity and specificity for enzyme-substrate interactions.
Environmental analysis employs this reagent to measure microbial activity and assess bioluminescent responses in aquatic and soil samples, aiding in ecological studies.
Pharmaceutical development benefits from D-(-)-Luciferin’s use in enzyme assays, supporting drug discovery and the evaluation of enzyme inhibitors and substrates.
Diagnostic testing incorporates this compound in assays that require precise light emission measurements, enhancing the accuracy of clinical and research diagnostics.
Biochemical research relies on D-(-)-Luciferin for studying enzyme kinetics and substrate interactions, providing insights into metabolic pathways and enzymatic mechanisms.

From the TCI brochure

Trace detection of ATP
Activity measurement of nucleotide phosphatase and others

Brand	TCI
CAS number	2591-17-5
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Enzymes, Enzyme Inhibitors, Enzyme Substrates
Pack sizes	Available in various quantities as per supplier specifications
Physical form	Solid
Storage	Must be stored in a cool, dark place away from light and oxidizing agents

Data from the TCI brochure

Emission wavelength	562 nm

Source: TCI brochure L3036 (2025-01-23)

D-(-)-Luciferin should be stored in a cool, dark environment to prevent degradation due to light exposure and oxidation. It is recommended to use airtight containers to minimize contact with air and moisture, which can affect its stability. Laboratory personnel should handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. Due to its sensitivity, it is important to maintain a controlled storage environment and avoid prolonged exposure to heat or light. Proper storage ensures the material remains effective for its intended applications, supporting accurate and reliable experimental results.

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