TBPE (=Tetrabromophenolphthalein Ethyl Ester Potassium Salt) [Sensitive spectrophotometric reagent for amines, quaternary ammonium salts and other cations] TCI A5107

Chemical Identity

Other names: TBPE
CAS No.: 62637-91-6
PubChem: CID 23689366·SID 87563125
Formula: C22H13Br4KO4
Molecular weight: 700.0 g/mol
Purity: >98.0%(HPLC)
Reference databases: ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: potassium 2,6-dibromo-4-[(3,5-dibromo-4-oxocyclohexa-2,5-dien-1-ylidene)-(2-ethoxycarbonylphenyl)methyl]phenolate
SMILES: CCOC(=O)C1=CC=CC=C1C(=C2C=C(C(=O)C(=C2)Br)Br)C3=CC(=C(C(=C3)Br)[O-])Br.[K+]
InChIKey: WCIQBKUTYDIBJC-UHFFFAOYSA-M

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Tetrabromophenolphthalein Ethyl Ester Potassium Salt (TBPE) is a highly sensitive spectrophotometric reagent used in analytical chemistry to detect and quantify amines, quaternary ammonium salts, and other cations. It plays a crucial role in laboratory settings where precise and reliable analytical results are required. This reagent is widely utilized in quantitative analysis due to its ability to produce a visible color change when reacting with target ions, making it an essential tool for spectroscopic methods. Its application extends across various analytical procedures, supporting both research and industrial testing.

TBPE is favored for its high sensitivity and strong reactivity with a wide range of organic and inorganic compounds. It maintains chemical stability under controlled conditions, ensuring consistent performance during analysis. The reagent’s ability to respond to various cations makes it versatile for different analytical applications. Its resistance to environmental factors such as light and air further enhances its reliability and shelf life when stored properly. These properties make TBPE a preferred choice for laboratories requiring accurate and reproducible results.

In Indonesian laboratories, TBPE is commonly used in research institutions and chemical industries for analytical testing. Its application is particularly relevant in environmental, pharmaceutical, and food industries, where the detection of cations is critical. The reagent’s ease of use and accuracy contribute to its widespread adoption in both academic and industrial settings, supporting a wide range of analytical needs.

TCI brochures (PDF)

Titration Reagents and TLC Stains 2026-05-07 · p. 3

Related TCI products

Environmental analysis for detecting trace levels of cations in water and soil samples due to its high sensitivity and reliable color response.
Pharmaceutical research to quantify amines and quaternary ammonium compounds in drug formulations and quality control processes.
Food safety testing for identifying harmful cations in food products, ensuring compliance with safety standards and regulations.
Industrial process control for monitoring the presence of specific ions in chemical manufacturing and wastewater treatment.
Academic research in analytical chemistry for developing and validating new spectrophotometric methods for ion detection.

Brand	TCI
CAS number	62637-91-6
Molecular formula	—
Purity	—
Category	Analytical Chemistry > Analytical Reagents > Application Specific Reagents
Pack sizes	Available in standard laboratory quantities as per supplier specifications
Physical form	Solid powder or crystalline, depending on packaging
Storage	Store in a cool, dry place away from light and moisture

TBPE should be stored in a cool, dry environment, away from direct sunlight and moisture to maintain its chemical stability and effectiveness. It is recommended to use airtight containers to prevent exposure to air and humidity, which could affect its performance. Proper labeling of storage containers is essential for safe handling and identification. In laboratory settings, it is important to avoid contact with incompatible substances and ensure adequate ventilation when handling. Regular inspection of storage conditions ensures the reagent remains in optimal condition for analytical use. Always follow standard safety protocols when working with chemical reagents to ensure a safe and controlled laboratory environment.

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