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TCI

CAS 378-44-9

Betamethasone TCI B1837

Betamethasone TCI B1837

Chemical Identity

CAS No.
378-44-9
PubChem
CID 9782·SID 87564725
Formula
C22H29FO5
Molecular weight
392.5 g/mol
Purity
>98.0%(HPLC)
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
SMILES
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
InChIKey
UREBDLICKHMUKA-DVTGEIKXSA-N
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Betamethasone is a synthetic steroid compound widely utilized in pharmacological and biochemical research. As a potent corticosteroid, it exhibits strong anti-inflammatory, immunosuppressive, and anti-allergic properties, making it a key reagent in experimental settings. Its ability to modulate immune responses and inflammatory processes makes it essential for studying cellular metabolism and the effects of steroids on biological systems. This compound is frequently employed in research aimed at understanding disease mechanisms and developing therapeutic interventions.

The chemical stability and solubility of betamethasone in organic solvents contribute to its versatility in laboratory applications. These characteristics allow it to be used in various experimental formats, including both liquid and solid forms. Its predictable behavior under different conditions ensures reliable results in experiments. Additionally, its specific biological activity makes it a preferred choice for studies involving endocrine systems and immune responses.

In Indonesian laboratories, betamethasone is commonly used in public health, pharmacology, and biomedical research. It plays a crucial role in drug effect studies, toxicity testing, and investigations into inflammatory and autoimmune diseases. Its consistent performance and well-documented properties make it a trusted reagent for researchers seeking accurate and reproducible results.

  • Pharmacological research utilizes betamethasone to study the effects of corticosteroids on inflammation and immune responses.
  • Biochemical experiments often involve betamethasone to explore steroid metabolism and cellular signaling pathways.
  • Toxicology studies benefit from betamethasone's ability to mimic natural corticosteroids in assessing drug safety and side effects.
  • Immunological research employs betamethasone to investigate immune suppression and its impact on disease progression.
  • Biomedical studies use betamethasone to develop and test new therapeutic agents for inflammatory and autoimmune conditions.

Brand TCI
CAS number 378-44-9
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents
Pack sizes Available in various quantities as per standard laboratory reagent packaging
Physical form Solid
Storage Store in a cool, dry place away from light and moisture

Betamethasone should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent contamination and degradation. Due to its potent biological activity, proper handling is essential to avoid exposure. Laboratory personnel should wear appropriate personal protective equipment when handling the compound. It is important to ensure that storage conditions are consistent to preserve the integrity of the reagent for experimental use. Always follow standard laboratory safety protocols when working with this compound to ensure safe and effective research outcomes.

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