Dexamethasone TCI D1961

Chemical Identity

CAS No.: 50-02-2
PubChem: CID 5743·SID 87568418
Formula: C22H29FO5
Molecular weight: 392.47 g/mol
Purity: >99.0%(HPLC)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
InChIKey: UREBDLICKHMUKA-CXSFZGCWSA-N
MDL: MDL00064136

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Dexamethasone is a synthetic corticosteroid widely used in biomedical and pharmacological research. As a derivative of glucocorticoids, it plays a crucial role in modulating immune responses and metabolic processes within laboratory settings. This compound is particularly valuable in organoid culture studies, where it supports the development and maintenance of human or animal tissue models. Its ability to influence cellular differentiation and create optimal culture environments makes it an essential tool for researchers working with complex biological systems.

Dexamethasone is preferred due to its potent anti-inflammatory properties and its capacity to suppress immune responses. These characteristics make it ideal for applications requiring the reduction of inflammation or the inhibition of T-cell activity. Its stability under certain conditions and ease of storage further enhance its utility across various research scales. The compound's versatility allows it to be used in a wide range of experimental designs, from disease modeling to drug testing, making it a staple in modern laboratory practices.

In Indonesian laboratories, Dexamethasone is commonly used in research related to autoimmune diseases, cancer, and inflammatory conditions. Its role in developing disease models and testing therapeutic effects has made it a key component in both academic and industrial research. The compound's reliability and consistent performance ensure that it remains a trusted reagent for scientists working in diverse fields of life sciences.

TCI brochures (PDF)

Xylem Differentiation-Inducing Polyamine Xylemin 2024-11-15 · p. 2
Bone Metabolism Research Reagents 2026-04-21 · p. 2
Organoid Research Reagents 2025-09-11 · p. 8
Regenerative Medicine Research Reagents 2016-03-18 · p. 1
Anti-Rheumatoid Arthritis Ingredients 2025-01-29 · p. 1
Steroids 2026-07-28 · p. 5

Related TCI products

Organoid Culture: Dexamethasone supports the development and maintenance of human and animal organoids by modulating cellular differentiation and creating optimal culture environments.
Disease Modeling: Its anti-inflammatory properties make it suitable for creating in vitro models of inflammatory and autoimmune diseases for research and drug development.
Immunomodulation Studies: The compound's ability to suppress immune responses is ideal for experiments involving T-cell inhibition and immune system modulation.
Drug Efficacy Testing: Dexamethasone is used to assess the effects of pharmaceutical compounds in controlled environments, particularly in inflammation-related conditions.
Tissue Engineering: It aids in the cultivation of engineered tissues by influencing cellular behavior and promoting the formation of functional tissue structures.

From the TCI brochure

Niche factor for hepatocyte differentiation (Table 1)

Brand	TCI
CAS number	50-02-2
Molecular formula	—
Purity	—
Category	Life Science > Cell Culture > Organoid Culture
Pack sizes	Available in various quantities as per standard laboratory supply options
Physical form	Solid powder
Storage	Store at controlled room temperature, away from moisture and light

Dexamethasone should be stored in a cool, dry place away from direct sunlight and moisture to maintain its stability and potency. It is recommended to use airtight containers to prevent contamination and degradation. In laboratory settings, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safety during preparation and use. Proper labeling of containers is essential for traceability and safe handling. Due to its chemical nature, it should be kept out of reach of children and stored in a secure location. Regular monitoring of storage conditions ensures the compound remains effective for research applications.

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