Bortezomib is a chemical compound widely used in pharmacological and biochemical research, particularly in the development of cancer treatments. As a pharmaceutical research reagent, it plays a crucial role in experimental studies aimed at understanding and combating diseases such as multiple myeloma and leukemia. This compound is essential for researchers seeking to explore the mechanisms of protein degradation and its impact on cellular processes. Its application extends to various laboratory settings where precision and reliability are paramount.
Bortezomib is preferred due to its high chemical stability under specific conditions and its excellent solubility in organic solvents like ethanol and dimethyl sulfoxide (DMSO). These properties make it highly versatile for use in a wide range of biochemical experiments. Additionally, its high purity ensures accurate and reproducible results, which are vital for scientific research. The compound’s ability to selectively inhibit proteasomes makes it a valuable tool for studying protein turnover and its implications in disease progression.
In Indonesian laboratories, bortezomib is commonly used by researchers and scientists to investigate the effects of pharmaceutical compounds on cells and to develop new therapeutic strategies. Its role in experimental drug testing and cellular research makes it a key component in the study of cancer biology and related fields. The compound’s reliability and effectiveness make it a preferred choice for those conducting advanced biochemical and pharmacological experiments.
- Pharmaceutical research for drug development and testing due to its ability to inhibit proteasomes and affect protein degradation pathways.
- Cancer cell studies focusing on multiple myeloma and leukemia as it targets abnormal protein accumulation in malignant cells.
- Biochemical experiments requiring high-purity reagents with consistent performance and solubility in organic solvents.
- Experimental models for understanding cellular responses to proteasome inhibitors in disease progression.
- Research applications in pharmacology where precise and reliable reagents are essential for accurate experimental outcomes.
| Brand | TCI |
|---|---|
| CAS number | 179324-69-7 |
| Molecular formula | — |
| Purity | — |
| Category | Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents |
| Pack sizes | As per supplier specifications |
| Physical form | Solid (as per standard product description) |
| Storage | Store in a cool, dry place away from light and moisture |
Bortezomib should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers made of glass or high-density polyethylene to prevent contamination and degradation. Due to its potential reactivity, it should be handled with appropriate personal protective equipment such as gloves and safety goggles. In laboratory settings, it should be stored separately from incompatible substances to ensure safety. Regular monitoring of storage conditions is advised to maintain the integrity and effectiveness of the compound during experimental use.
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