TCI B6377, N-benzylhydroxylamine (CAS 622-30-0), is a nitrogen–oxygen reagent widely used to generate nitrones by condensation with aldehydes and ketones. The resulting nitrones act as 1,3-dipoles in cycloaddition reactions, providing efficient access to isoxazolidine rings with useful regio- and stereocontrol. Reductive ring opening of those isoxazolidines then delivers valuable 1,3-amino alcohol motifs, while the benzyl group can be removed by hydrogenolysis to unmask the nitrogen. AMI Scientific supplies this TCI reagent in a 1 g pack size; as with hydroxylamine derivatives generally, cool storage in a tightly closed container is recommended.
—
| Brand | — |
|---|---|
| CAS number | — |
| Molecular formula | — |
| Purity | — |
| Category | — |
| Pack sizes | — |
| Physical form | — |
| Storage | — |
—
- Merino et al. (1999). ChemInform Abstract: Synthesis of Isoxazolidin‐5‐ones via Stereocontrolled Michael Additions of Benzylhydroxylamine to L‐Serine Derived α,β‐Unsaturated Esters.. ChemInform doi:10.1002/chin.199917133
- BONACCORSI et al. (1997). ChemInform Abstract: A Convenient Large Scale Synthesis of O‐Benzylhydroxylamine.. ChemInform doi:10.1002/chin.199728070
- Bonaccorsi et al. (1997). A Convenient Large Scale Synthesis of O-Benzylhydroxylamine. Synthetic Communications doi:10.1080/00397919708003349
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
Produk Terkait
-
O-ButylhydroxylamineHydrochloride TCI B5686
Regular price From Rp 1.485.750,00Regular price -
4-Bromo-N-methoxy-N-methylbenzamide TCI B5728
Regular price From Rp 1.670.550,00Regular price -
Bifenazate TCI B6341
Regular price Rp 7.234.500,00Regular price
