TCI B6448 2-Bromo-1,3,5-trimethoxybenzene (CAS 1131-40-4) is an electron-rich aryl bromide used as a non-heterocyclic building block. The bromine handle allows straightforward elaboration through palladium-catalyzed cross-coupling or conversion into organometallic reagents. Its trimethoxyphenyl core is frequently used in the synthesis of natural product analogues and medicinal chemistry intermediates. Handle the solid in a fume hood with standard personal protective equipment and store it tightly sealed in a cool, dry, dark place.
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