![Bicyclo[1.1.1]pentane-1,3-dicarboxylic Acid (CAS 56842-95-6) - TCI B6522 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510B6522.jpg?v=1767093799&width=1946)
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TCI B6522 Bicyclo[1.1.1]pentane-1,3-dicarboxylic Acid (CAS 56842-95-6) is a rigid, three-dimensional building block widely used in modern medicinal chemistry. The bicyclo[1.1.1]pentane core is frequently explored as a bioisostere for para-substituted benzene rings, offering a fixed linear vector between substituents. Its two bridgehead carboxylic acids can be converted into esters, amides, and rigid linkers for further elaboration. Supplied in a 1 g research pack, it should be weighed in a well-ventilated area and stored cool, dry, and tightly sealed.
TCI brochures (PDF)
- Bicycloalkane Building Blocks ― Benzene Bioisosteres ― 2025-04-01 · p. 1
- Monomers 2025-05-28 · p. 36
Related TCI products
- TCI M3149 83249-10-9 3-(Methoxycarbonyl)bicyclo[111]pentane-1-carboxylic Acid
- TCI D6351 115913-32-1 Dimethyl Bicyclo[1.1.1]pentane-1,3-dicarboxylate
- TCI D6184 303752-38-7 3-[(tert-Butoxycarbonyl)amino]bicyclo[1.1.1]pentane-1-carboxylic Acid
- TCI B6619 22287-28-1 Bicyclo[1.1.1]pentane-1-carboxylic Acid
- TCI B5595 711-02-4 Bicyclo[2.2.2]octane-1,4-dicarboxylic Acid
- TCI M3710 65862-01-3 3-Methylbicyclo[1.1.1]pentane-1-carboxylic Acid
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References cited in the TCI brochure
- Murugaiah A. M. Subbaiah. Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design Journal of Medicinal Chemistry, 2021. doi:10.1021/acs.jmedchem.1c01215
Product Categories
- Building BlocksNon-Heterocyclic Building BlocksCarbonyl Compounds [Non-Heterocyclic Building Blocks]
- Building BlocksSpecialized Building Blocks for Drug DiscoveryBicyclo[1.1.1]pentane Building Blocks
- Pharmaceutical Development and Drug Discovery Research ReagentsSpecialized Building Blocks for Drug DiscoveryBicyclo[1.1.1]pentane Building Blocks
Produk Terkait
-
3-(Methoxycarbonyl)bicyclo[111]pentane-1-carboxylicAcid TCI M3149
Regular price From Rp 955.500,00Regular price -
DimethylBicyclo[1.1.1]pentane-1,3-dicarboxylate TCI D6351
Regular price Rp 3.260.250,00Regular price -
3-[(tert-Butoxycarbonyl)amino]bicyclo[1.1.1]pentane-1-carboxylicAcid TCI D6184
Regular price From Rp 2.174.550,00Regular price -
Bicyclo[1.1.1]pentane-1-carboxylicAcid TCI B6619
Regular price Rp 9.116.100,00Regular price -
Bicyclo[2.2.2]octane-1,4-dicarboxylicAcid TCI B5595
Regular price Rp 4.957.050,00Regular price -
3-Methylbicyclo[1.1.1]pentane-1-carboxylicAcid TCI M3710
Regular price Rp 6.758.850,00Regular price -
[1,1'-Biphenyl]-3,3'-dicarboxylicAcid TCI B7024
Regular price From Rp 1.273.650,00Regular price -
Bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylicAnhydride TCI B3038
Regular price Rp 3.605.700,00Regular price
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