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TCI

CAS 22287-28-1

Bicyclo[1.1.1]pentane-1-carboxylic Acid TCI B6619

Bicyclo[1.1.1]pentane-1-carboxylic Acid TCI B6619
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Description

TCI B6619 is bicyclo[1.1.1]pentane-1-carboxylic acid, a monofunctional derivative of the widely studied BCP cage. The bridgehead-to-bridgehead axis of bicyclo[1.1.1]pentane closely mimics the linear geometry of para-substituted benzene rings, making it a favoured aromatic bioisostere. Replacing arenes with BCP units is frequently associated with improved aqueous solubility, reduced lipophilicity, and enhanced metabolic stability. AMI Scientific supplies this TCI building block in a 100 mg pack size for drug discovery and organic synthesis laboratories.

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