TCI B6555 is 2,8-bis(trifluoromethoxy)dibenzothiophene, a fluorinated tricyclic building block carrying two OCF₃ groups on a sulfur-containing conjugated core. Trifluoromethoxy substituents are highly valued for the metabolic stability and lipophilicity they impart in medicinal chemistry, and for the electronic tuning they provide in organic materials. Its symmetric substitution pattern simplifies downstream functionalisation, while the sulfur centre can be oxidised to the sulfoxide or sulfone to modulate electronic properties. AMI Scientific supplies this TCI product in 1 g and 10 g pack sizes; consult the official TCI documentation and safety data sheet before use.
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- RUZICKA et al. (1996). ChemInform Abstract: Synthesis and Toxicity of 1,2‐Bis(trifluoromethoxy)‐1,1,3,3,3‐ pentafluoropropane.. ChemInform doi:10.1002/chin.199629081
- Ruzicka et al. (1996). Synthesis and toxicity of 1,2-bis(trifluoromethoxy)-1,1,3,3,-pentafluoropropane. Journal of Fluorine Chemistry doi:10.1016/0022-1139(95)03374-2
- Mudshinge et al. (2022). Synthesis and applications of S-(trifluoromethyl)-2,8-bis(trifluoromethoxy)dibenzothiophenium triflate (Umemoto reagent IV). Journal of Fluorine Chemistry doi:10.1016/j.jfluchem.2022.110015
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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