TCI
tert-Butyl 2-Methylpiperazine-1-carboxylate TCI B6870
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Description
TCI B6870 (CAS 120737-78-2) is tert-butyl 2-methylpiperazine-1-carboxylate, a mono-Boc-protected piperazine bearing a methyl substituent at the 2-position. The protected nitrogen allows chemists to functionalise the remaining secondary amine selectively through alkylation, acylation, sulfonylation or reductive amination. The Boc group can subsequently be removed under acidic conditions to reveal the second nitrogen for further elaboration. Supplied by TCI in 5 g and 25 g pack sizes, it should be stored cool and dry and kept away from strong acids.
Scientific References
- Studer et al. (1995). Synthesis and First Applications of a New Chiral Auxiliary (tert‐butyl 2‐(tert‐butyl)‐5,5‐dimethyl‐4‐oxoimidazolidine‐1‐carboxylate). Helvetica Chimica Acta doi:10.1002/hlca.19950780512
- (2002). PREPARATION AND DIELS-ALDER REACTION OF A 2-AMIDO SUBSTITUTED FURAN: tert-BUTYL 3a-METHYL-5-OXO-2,3,3a,4,5,6-HEXAHYDROINDOLE-1-CARBOXYLATE. Organic Syntheses doi:10.15227/orgsyn.078.0202
- STUDER et al. (1995). ChemInform Abstract: Synthesis and First Applications of a New Chiral Auxiliary (tert‐Butyl 2‐(tert‐Butyl)‐5,5‐dimethyl‐4‐oxoimidazolidine‐1‐carboxylate) (V).. ChemInform doi:10.1002/chin.199547157
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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