4'-Chloroacetophenone (TCI C0033, CAS 99-91-2) is a chlorinated aromatic ketone valued as a versatile synthetic building block. Its acetyl group supports aldol condensations, alpha-functionalisation, and reductions, while the para chlorine enables palladium-catalysed cross-coupling. It is commonly used to prepare chalcones, heterocycles, and chiral alcohol intermediates. Offered in 25 g, 100 g, and 500 g packs, it should be weighed in a fume hood with proper protective equipment and stored tightly closed in a cool, dry, light-protected place.
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- Department of Physics, Assam University et al. (2014). Investigations of electronic, chemical and non-linear optical properties of para-chloroacetophenone and meta-chloroacetophenone using density functional theory. SOP Transactions on Physical Chemistry doi:10.15764/pche.2014.02007
- Chanysheva et al. (2021). Asymmetric Bioreduction of 4-Chloroacetophenone Catalyzed by Daucus carota Cells in Water and Organic Solvents. Russian Journal of General Chemistry doi:10.1134/s1070363221130247
- Devi (2010). Vibrational relaxation study in 4-chloroacetophenone. Indian Journal of Physics doi:10.1007/s12648-010-0093-0
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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