TCI C0276 3-Chloropropionic Acid (CAS 107-94-8) is the beta-chlorinated isomer of chloropropionic acid and serves as a flexible three-carbon building block. The chlorine at the beta position can be displaced by nucleophiles or eliminated to generate unsaturated carbonyl systems used as Michael acceptors. Its carboxyl group remains available for esterification, amidation, or conversion to the corresponding acid chloride for Friedel–Crafts chemistry. AMI Scientific offers this TCI reagent in 25 g and 500 g packs for organic synthesis and materials research laboratories.
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- EDBEİB (2020). 3-Chloropropionic Acid (3cp) Degradation and Production of Propionic Acid by Newly Isolated Fungus Trichoderma Sp. Mf1. International Journal of Life Sciences and Biotechnology doi:10.38001/ijlsb.677005
- DEVERA (2004). Putrescine as a marker of the effects of 2-chloropropionic acid in the rat brain. Neuroscience Letters doi:10.1016/s0304-3940(04)00314-3
- Holmberg et al. (1992). Alcohol Induced Reversal of Enantioselectivity in a Lipase Catalyzed Resolution of 2-Chloropropionic Acid. Biocatalysis doi:10.3109/10242429209014875
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