TCI C0287 5-Chlorosalicylic Acid (CAS 321-14-2) is a chlorinated salicylic acid featuring adjacent carboxyl and phenolic hydroxyl groups. This arrangement supports intramolecular hydrogen bonding and makes the compound an effective chelating ligand for transition metal ions. It is routinely used to prepare esters, amides, and other salicylate derivatives, and also serves as a linker in coordination polymer and metal–organic framework research. AMI Scientific provides this TCI building block in 25 g and 500 g packs for synthetic, coordination, and analytical chemistry laboratories.
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- Sofia (2008). Comparative Antiphlogistic Activity of Meseclazone, 5-Chlorosalicylic Acid, Acetylsalicylic Acid, Phenylbutazone, Indomethacin and Hydrocortisone in Various Rat Paw Edema Models. Pharmacology doi:10.1159/000136760
- Dr.Hemendra H Bhatt (2020). A Photophysical and Computational Study of 5-Chlorosalicylic Acid and Derivatives Featuring Thiadiazole, Oxadiazole, and Triazole Scaffolds. Vidhyayana doi:10.58213/9k1rtq07
- Kök (2020). Improving of callus formation in ‘Syrah’/‘110R’ combination by 5-chlorosalicylic acid and thidiazuron treatments. Acta Horticulturae doi:10.17660/actahortic.2020.1276.14
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