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Description
TCI C0512 Cyclopentanecarboxylic Acid (CAS 3400-45-1) is an aliphatic carboxylic acid bearing a carboxyl group directly on a cyclopentane ring. The acid handle is readily converted into esters, amides, acid chlorides, and other acyl derivatives using standard coupling protocols. Its rigid cyclopentyl motif appears frequently in pharmaceutical candidates, making it a practical building block for medicinal chemistry and analog library work. AMI Scientific supplies this TCI grade in 5 g and 25 g packs, and the material should be handled as a corrosive solid-phase reagent with appropriate protective equipment.
Scientific References
Kushev et al. (1999). Synthesis, Cytotoxicity and Antitumor Activity of Platinum(II) Complexes of Cyclopentanecarboxylic Acid Hydrazide. Biological Chemistrydoi:10.1515/bc.1999.164
Park et al. (2024). Exploring helix structures of γ‐peptides based on 2‐(aminomethyl)cyclopentanecarboxylic acid. Biopolymersdoi:10.1002/bip.23575
Mahmoudian et al. (1992). Resolution of 4-amino-cyclopentanecarboxylic acid methyl esters using hydrolytic enzymes. Enzyme and Microbial Technologydoi:10.1016/0141-0229(92)90055-s
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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