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TCI

CAS 627-00-9

4-Chlorobutyric Acid TCI C0651

4-Chlorobutyric Acid TCI C0651
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TCI C0651 4-Chlorobutyric Acid is a short-chain bifunctional building block bearing both a carboxylic acid and a terminal alkyl chloride. This arrangement provides complementary nucleophilic and electrophilic centres within a single molecule, making it especially useful for intramolecular cyclisation. The four-carbon spacing favours formation of stable five-membered rings, giving convenient access to lactone and lactam derivatives. AMI Scientific supplies this TCI product in 25 g and 500 g packs; it is corrosive and should be handled in a fume hood with appropriate protective equipment.

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  • Hayashi et al. (2024). Unique reaction of layered double hydroxides with 4-chlorobutyric acid. Applied Clay Science doi:10.1016/j.clay.2024.107322
  • Martínez‐Palau et al. (2005). Poly[(4‐hydroxybutyric acid)‐alt‐(glycolic acid)]: Synthesis by Thermal Polycondensation of Metal Salts of 4‐Chlorobutyric Acid Carboxymethyl Ester. Macromolecular Chemistry and Physics doi:10.1002/macp.200500260
  • Caira et al. (1996). Resolution of optical isomers of 4-amino-p-chlorobutyric acid lactam by co-crystallization. Journal of Chemical Crystallography doi:10.1007/bf01677103

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.