TCI C0651 4-Chlorobutyric Acid is a short-chain bifunctional building block bearing both a carboxylic acid and a terminal alkyl chloride. This arrangement provides complementary nucleophilic and electrophilic centres within a single molecule, making it especially useful for intramolecular cyclisation. The four-carbon spacing favours formation of stable five-membered rings, giving convenient access to lactone and lactam derivatives. AMI Scientific supplies this TCI product in 25 g and 500 g packs; it is corrosive and should be handled in a fume hood with appropriate protective equipment.
—
| Brand | — |
|---|---|
| CAS number | — |
| Molecular formula | — |
| Purity | — |
| Category | — |
| Pack sizes | — |
| Physical form | — |
| Storage | — |
—
- Hayashi et al. (2024). Unique reaction of layered double hydroxides with 4-chlorobutyric acid. Applied Clay Science doi:10.1016/j.clay.2024.107322
- Martínez‐Palau et al. (2005). Poly[(4‐hydroxybutyric acid)‐alt‐(glycolic acid)]: Synthesis by Thermal Polycondensation of Metal Salts of 4‐Chlorobutyric Acid Carboxymethyl Ester. Macromolecular Chemistry and Physics doi:10.1002/macp.200500260
- Caira et al. (1996). Resolution of optical isomers of 4-amino-p-chlorobutyric acid lactam by co-crystallization. Journal of Chemical Crystallography doi:10.1007/bf01677103
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
