TCI C0730 1,4-Cyclohexanedione (CAS 637-88-7) is a symmetrical cyclic diketone and one of the most versatile non-heterocyclic building blocks available. Its two opposed carbonyl groups provide a convenient platform for condensation, olefination, reductive amination, and selective ketal protection. Chemists rely on it for pharmaceutical intermediates, liquid-crystal precursors, spiro and macrocyclic frameworks, and polymer research. AMI Scientific offers 25 g and 500 g packs; store the crystalline solid tightly closed in a cool, dry place and weigh it with suitable protective equipment.
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- Wang et al. (1997). Cross-Resistance to Aryloxyphenoxypropionate and Cyclohexanedione Herbicides in Foxtail Millet (Setaria italica). Pesticide Biochemistry and Physiology doi:10.1006/pest.1997.2309
- Sohail et al. (2023). Limiting the Loading of Reactant 1,3-Cyclohexanedione Enables the Use of Less Catalyst. The Journal of Organic Chemistry doi:10.1021/acs.joc.3c00838
- Shen et al. (2011). The molecular structures and conformational compositions of 1,3 cyclohexanedione and 1,4 cyclohexanedione as determined by gas-phase electron diffraction and theoretical calculation. Journal of Molecular Structure doi:10.1016/j.molstruc.2011.08.043
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